3 t mr750 system

Manufactured by GE Healthcare

The GE Healthcare 3 T MR750 system is a magnetic resonance imaging (MRI) scanner that operates at a field strength of 3 Tesla. It is designed for clinical diagnostic imaging applications.

Automatically generated - may contain errors

Lab products found in correlation

Buscopan, by Boehringer Ingelheim (1 mentions) Twin speed gradients, by GE Healthcare (1 mentions) 8 channel head coil, by GE Healthcare (1 mentions) Ivis lumina xrms in vivo imaging system, by PerkinElmer (1 mentions) Ivis lumina xrms scanner, by PerkinElmer (1 mentions) Living image software, by PerkinElmer (1 mentions)

Close spelling variants of this product

Discovery MR750 3.0 T MR system GE Discovery MR750 3.0 T System Discovery MR750 3.0 T system GE DISCOVERY MR750 3-T MR system MR750 system MR750

4 protocols using 3 t mr750 system

Multiparametric MRI for Prostate Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

Patients underwent prostate MRI on a 3 T MR750 system (GE Healthcare, Waukesha, WI) using a 32-channel receiver coil. Intravenous injection of hyoscine butylbromide (Buscopan, 20 mg ml⁻¹; Boehringer Ingelheim, Ingelheim am Rhein, Germany) was administered prior to imaging unless clinically contraindicated. Multiparametric MRI protocol included axial T₁ weighted imaging, multiplanar high-resolution T₂ weighted two-dimensional (2D) fast recovery fast spin echo (FSE), spin-echo echoplanar imaging pulse diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) imaging, as described previously.^{25 (link)} DWI was performed with b-values: b-150, b-750, and b-1,000; with additional small field of view DWI obtained using b-2,000s/mm²; ADC maps were automatically calculated. Follow-up studies did not include post-contrast DCE sequences, but the protocol was otherwise identical for all patients and all scans included in the analysis.

Sushentsev N., Caglic I., Rundo L., Kozlov V., Sala E., Gnanapragasam V.J, & Barrett T. (2021). Serial changes in tumour measurements and apparent diffusion coefficients in prostate cancer patients on active surveillance with and without histopathological progression. The British Journal of Radiology, 95(1131), 20210842.

+ Open protocol

+ Expand

Structural Brain Imaging with 3T MRI

Check if the same lab product or an alternative is used in the 5 most similar protocols

All scanning was conducted on a General Electric 3T MR750 System (General Electric Healthcare, Milwaukee, WI) with Twin Speed gradients and a GE 8-channel head coil at the Center of Functional MRI at UCSD. See the supplement for more details.

Ho T.C., Connolly C.G., Blom E.H., LeWinn K.Z., Strigo I.A., Paulus M.P., Frank G., Max J.E., Wu J., Chan M., Tapert S.F., Simmons A.N, & Yang T.T. (2014). Emotion-dependent functional connectivity of the default mode network in adolescent depression. Biological psychiatry, 78(9), 635-646.

+ Open protocol

+ Expand

Multimodal MRI Imaging Protocol for Brain Evaluation

Check if the same lab product or an alternative is used in the 5 most similar protocols

All MRI data were acquired on a 3T MR750 system (GE Healthcare, Milwaukee, WI) using a 16-channel head, neck, and spine array coil. The multimodal MRI protocol included a pre-contrast T1-weighted fast spoiled gradient echo (FSPGR) sequence (T1w), a T2-weighted PROPELLER sequence (T2w), and a fluid-attenuated inversion recovery (FLAIR) sequence which were followed by a gadolinium (Gd)-enhanced T1-weighted FSPGR sequence (T1c). All imaging parameters are shown in Table 2.Table 2

MR sequence parameters

	3D QTI	T1-weighted FSPGR (T1w)	Gd-enhanced T1-weighted FSPGR (T1c)	T2-weighted PROPELLER (T2w)	CUBE FLAIR (FLAIR)
Acquisition	3D	3D	3D	2D	3D
Native resolution (mm³)	1.125 × 1.125 × 1.125	0.47 × 0.47 × 0.8	0.47 × 0.47 × 0.8	0.5 × 0.5 × 3.3	0.8 × 0.47 × 0.47
Matrix size	200 × 200 × 200	512 × 512 × 212	512 × 512 × 212	512 × 512 × 46	192 × 512 × 512
Field of view (mm³)	225 × 225 × 225	240 × 240 × 170	240 × 240 × 170	260 × 260 × 152	154 × 240 × 240
Slices	-	-	-	46	-
Native slice thickness (mm)	-	-	-	3.0	-
TE (ms)	1.8	2.1	2.1	120.7	92
TR (ms)	7.8	4.6	7.1	5751	5002
TI (ms)	18	-	-	-	1701
ɑ (°)	0.8 ≤ ɑ ≤ 70	12	12	160	90
Acquisition time (min)	6:25	1:54	4:43	5:15	4:48

Pirkl C.M., Nunez-Gonzalez L., Kofler F., Endt S., Grundl L., Golbabaee M., Gómez P.A., Cencini M., Buonincontri G., Schulte R.F., Smits M., Wiestler B., Menze B.H., Menzel M.I, & Hernandez-Tamames J.A. (2021). Accelerated 3D whole-brain T1, T2, and proton density mapping: feasibility for clinical glioma MR imaging. Neuroradiology, 63(11), 1831-1851.

+ Open protocol

+ Expand

Quantifying CAR-T Cell Cytotoxicity and Detection

Check if the same lab product or an alternative is used in the 5 most similar protocols

To compare the cytotoxicity of PFC + and unlabeled CAR-T cells, 5 × 10⁴ NALM6-tdT-FLuc cells were seeded with PFC + or unlabeled CAR-T cells at increasing effector to target ratios (1:4, 1:2, 1:1). Twenty-four hours later, 1 µL of D-luciferin was added to each well (30 mg/ml, Syd Labs), and BLI was performed immediately on an IVIS Lumina XRMS scanner (IVIS Lumina XRMS In Vivo Imaging System, PerkinElmer). BLI signal was evaluated with region-of-interest (ROI) analysis using Living Image Software (PerkinElmer). Quantification was performed by drawing ROIs over each well to obtain the average radiance per well (photons/second/mm²/steradian).
To evaluate the minimum number of PFC + CAR-T cells that could be detected at 3 T, triplicates of CAR-T cell pellets containing decreasing numbers of labeled cells (2, 1, 0.5, 0.25, 0.1 (× 10⁶) cells) were imaged using ¹⁹F MRI. Samples were made by mixing labeled and unlabeled CAR-T cells to obtain a total of 2 × 10⁶ cells per Eppendorf tube; the Eppendorf tube was then spun down to form pellets and then covered with 1% agarose prior to MRI. The resulting samples were imaged at 3 T using a clinical GE 3 T MR750 system following the same imaging protocols used for in vivo imaging (see below). Analysis of all ¹⁹F MRI images is described further below.

Dubois V.P., Sehl O.C., Foster P.J, & Ronald J.A. (2021). Visualizing CAR-T cell Immunotherapy Using 3 Tesla Fluorine-19 MRI. Molecular Imaging and Biology, 24(2), 298-308.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!