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Chrompure whole rat igg

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ChromPure whole rat IgG is a laboratory reagent that provides a source of purified rat immunoglobulin G (IgG) molecules. It is produced by isolating and purifying the IgG fraction from rat serum or plasma.

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Lab products found in correlation

Rat anti cd8α yts169.4, by BioXCell (2 mentions) Absolute count standard, by Bangs Laboratories (1 mentions) Rat anti cd4 gk1, by BioXCell (1 mentions)

Spelling variants of this product

ChromPure (6 citations) ChromPure Rat IgG (2 citations) ChromPure Rat IgG Whole Molecule (2 citations)

3 protocols using chrompure whole rat igg

1

Rat Anti-CD8α Depletion in Mice

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Mice were injected i.p. with 250 μg rat anti-CD8α (YTS169.4; Bio X Cell, West Lebanon NH) or ChromPure whole rat IgG (Jackson ImmunoResearch Laboratories, West Grove PA) at 10, 12, 19, and 26 days p.i. Depletion was confirmed in the blood by flow cytometry Absolute Count Standard (Bangs Laboratories, Fishers IN).
Maru S., Jin G., Schell T.D, & Lukacher A.E. (2017). TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection. PLoS Pathogens, 13(4), e1006318.
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2

CD8+ and CD4+ T Cell Depletion

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Mice were injected i.p. with 250-µg rat anti-CD8α (YTS169.4; Bio X Cell, West Lebanon, NH), rat anti-CD4 (GK1.5; Bio X Cell, West Lebanon, NH), or ChromPure whole-rat IgG (Jackson ImmunoResearch Laboratories, West Grove, PA) at 21, 23, 30, 37, and 44 days p.i. T cell depletion was confirmed in blood by flow cytometry using Absolute Count Standards (Bangs Laboratories, Fishers, IN).
Maru S., Jin G., Desai D., Amin S., S.h.w.e.t.a.n.k., Lauver M.D, & Lukacher A.E. (2017). Inhibition of Retrograde Transport Limits Polyomavirus Infection In Vivo. mSphere, 2(6), e00494-17.
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3

CD4+ and CD8+ T Cell Depletion

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Mice were injected i.p. with 250 µg of rat anti-CD8 (YTS169.4, BioXCell, West Lebanon, NH), rat anti-CD4 (GK1.5, BioXCell), or ChromPure whole rat IgG (Jackson ImmunoResearch, West Grove, PA) at 10 and 12 dpi, then weekly until 60 dpi. Lack of staining of PBMCs by anti-CD4 (RM4–5) or anti-CD8β (53–5.8) confirmed depletion.
Frost E.L., Kersh A.E., Evavold B.D, & Lukacher A.E. (2015). Resident-memory CD8 T cells express high-affinity T cell receptors. Journal of immunology (Baltimore, Md. : 1950), 195(8), 3520-3524.
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