Thermocool ablation catheter

Manufactured by Johnson & Johnson

Sourced in United States

The ThermoCool ablation catheter is a medical device used in electrophysiology procedures. It is designed to deliver radiofrequency energy to targeted areas of the heart, enabling the controlled ablation of cardiac tissue. The catheter features a temperature-sensing tip that monitors the temperature during the ablation process.

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Thermocool (61 citations) Navistar RMT ThermoCool ablation catheter (2 citations) ThermoCool SmartTouch Ablation Catheter (2 citations)

2 protocols using thermocool ablation catheter

Ablation of Ventricular Ectopic Foci

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The PVC origin was confirmed by intra-cardiac electrophysiological study in all patients. All patients underwent electrophysiological study after five half-lives of antiarrhythmic drug withdrawal. If PVCs were absent, isoproterenol (1.0–3.0 μg/min) was administered intravenously until constant and measurable PVCs were obtained. The right femoral vein was routinely punctured, and a cold saline perfusion ablation catheter (ThermoCool ablation catheter, Biosense Webster, United States) or ST large-tip catheter was delivered via an 8F vascular sheath to the RVOT; for the LVOT, the catheter was delivered retrograde via femoral artery puncture. The target site for RFCA was determined by a combination of activation mapping (earliest local activation time preceding QRS onset by ≥20 ms) during PVCs/IVTs and pace mapping (pacing marker was identical to the QRS pattern in ≥ 11 leads of the 12-lead ECG of a clinical PVC) (Yamada et al., 2007 (link)).

Zhao L., Li R., Zhang J., Xie R., Lu J., Liu J., Miao C, & Cui W. (2022). The R-S difference index: A new electrocardiographic method for differentiating idiopathic premature ventricular contractions originating from the left and right ventricular outflow tracts presenting a left bundle branch block pattern. Frontiers in Physiology, 13, 1002926.

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Cardiac Electrophysiology Mapping Protocols

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Electroanatomic mapping (“EAM mesh”) of the LV was performed with CARTO 3 using either a PentaRay multipolar catheter or Thermocool ablation catheter (Biosense Webster, Diamond Bar, CA) and registered to a CT-derived LV mesh (“CARTO CT mesh”) using landmark followed by surface registration. The PentaRay catheter available at our institution has 1 mm electrode size with 4 electrodes per spline with inter-electrode spacing of 4 mm. Bipolar electrograms were recorded between adjacent electrodes with two bipoles per spline (e.g. 1,2 and 3,4). The Thermocool ablation catheter has a 3.5 mm tip electrode and a 2 mm proximal electrode with an inter-electrode spacing of 2 mm.
Bipolar and unipolar electrograms were filtered at 10 to 400 Hz and 1 to 240 Hz, respectively, and recorded as the difference between the highest and lowest deflections of a stable contact signal. Electrogram duration was manually measured from the onset to the end of electrogram deflections at 400 mm/s speed. In accepting the electrogram at each EAM point, we confirmed that ≥2 consecutive electrograms had the same morphology to avoid electrogram artifact due to poor catheter contact.

Misra S., Zahid S., Prakosa A., Saju N., Tandri H., Berger R.D., Marine J.E., Calkins H., Zipunnikov V., Trayanova N., Zimmerman S.L, & Nazarian S. (2018). The Field of View of Mapping Catheters Quantified by Electrogram Associations with Radius of Myocardial Attenuation on Contrast-Enhanced Cardiac Computed Tomography. Heart rhythm, 15(11), 1617-1625.

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