Na methanesulfonate

Manufactured by Merck Group

Sourced in United States

Na-methanesulfonate is a laboratory reagent used in various chemical reactions and analyses. It is a sodium salt of methanesulfonic acid and serves as a source of sodium and sulfonate ions. The core function of Na-methanesulfonate is to provide a soluble, ionic form of the methanesulfonate group for use in chemical procedures. It is commonly utilized in research and analytical settings where the controlled introduction of these ions is required.

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Lab products found in correlation

Cs methanesulfonate, by Merck Group (3 mentions) Cs bapta, by Thermo Fisher Scientific (2 mentions) Gdcl3, by Thermo Fisher Scientific (2 mentions) Arachidonic acid, by Merck Group (1 mentions) 2 aminoethoxydiphenyl borate 2 apb, by Merck Group (1 mentions) Nordihydroguaiaretic acid, by Merck Group (1 mentions) Adenosine 5 triphosphate magnesium salt, by Merck Group (1 mentions)

3 protocols using na methanesulfonate

Fura-5F-AM Calcium Signaling Assay

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Arachidonic acid, Cs-methanesulfonate and Na-methanesulfonate were purchased from Sigma. Fura-5F-AM was purchased from Setareh Biotech, LLC. 2-aminoethoxydiphenyl borate (2-APB) was purchased from Calbiochem. Cs-BAPTA was purchased from Invitrogen. GdCl₃ was from Acros Organics. All dicer-substrate siRNAs (dsiRNAs) were purchased from IDT. The transfection kit (VCA-1003) for HEK293 cells was from Lonza. All other chemicals were from Fisher.

Desai P.N., Zhang X., Wu S., Janoshazi A., Bolimuntha S., Putney J.W, & Trebak M. (2015). Multiple Types of Calcium Channels Arising from Alternative Translation Initiation of the Orai1 Message. Science signaling, 8(387), ra74.

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Reagents for Ion Channel Studies

Cited 3 times

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AA, Cs-methanesulfonate, Na-methanesulfonate, and nordihydroguaiaretic acid (NDGA) were purchased from Sigma-Aldrich. LTC₄, N-methyl LTC₄ (NMLTC₄), and eicosatetraynoic acid (ETYA) were from Cayman. 2-Aminoethoxydiphenyl borate (2-APB) was purchased from EMD Millipore. Cs-1,2-bis-(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (Cs-BAPTA) was purchased from Invitrogen. GdCl₃ was from Acros Organics. All small interference RNAs (siRNAs) were purchased from Dharmacon and have been described previously (Abdullaev et al., 2008 (link); González-Cobos et al., 2013 (link); Motiani et al., 2013 (link); Shinde et al., 2013 (link); see also Table S1). The transfection kits (VCA-1003 for HEK293 cells and VPI-1004 for VSMCs) were from Lonza. All other chemicals were from Thermo Fisher Scientific.

Zhang X., Zhang W., González-Cobos J.C., Jardin I., Romanin C., Matrougui K, & Trebak M. (2014). Complex role of STIM1 in the activation of store-independent Orai1/3 channels. The Journal of General Physiology, 143(3), 345-359.

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Electrophysiological Recording Solutions

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Salts for physiological recordings were of the highest grade and purchased from SigmaAldrich, Fisher Scientific or BDH. Na-methanesulfonate, Adenosine 5′ -triphosphate magnesium salt and Cs-methanesulfonate and salts for internal solutions were from Sigma (St. Louis, MO, USA). Cs-BAPTA and Ca²⁺-sensitive fluorescent indicators were from Invitrogen (Eugene, OR, USA). Sources for other reagents used are indicated where described.

Pierro C., Zhang X., Kankeu C., Trebak M., Bootman M.D, & Roderick H.L. (2018). Oncogenic KRAS suppresses store-operated Ca2+ entry and ICRAC through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines.. Cell calcium, 72, 70-80.

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