Silymarin 98

Manufactured by Merck Group

Sourced in Germany

Silymarin 98% is a highly purified extract from the seeds of the milk thistle plant. It is a complex of flavonolignans and contains predominantly silymarin, with a minimum purity of 98%. Silymarin 98% is a standardized, high-quality product suitable for use in various applications.

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Lab products found in correlation

Carboxymethylcellulose, by Merck Group (2 mentions) Tnf α sc 52746, by Santa Cruz Biotechnology (1 mentions) Bisphenol a 99, by Merck Group (1 mentions)

2 protocols using silymarin 98

Bisphenol A, Silymarin, and Carboxymethyl Cellulose Assay

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Bisphenol A 99%, silymarin 98% and carboxymethyl cellulose were purchased from Sigma-Aldrich Chemie GmbH (Munich, Germany). TNF-α (sc-52746) and IL-6 (sc-1265-R) antibodies were supplied by Santa Cruz Biotechnology, Inc. (Dallas, TX, USA). A Novocastra kit for immunohistochemistry (Novolink Max Polymer Detection System; RE7280-K) was purchased from Leica Microsystems GmbH (Wetzlar, Germany).

Zaulet M., Kevorkian S.E., Dinescu S., Cotoraci C., Suciu M., Herman H., Buburuzan L., Badulescu L., Ardelean A, & Hermenean A. (2017). Protective effects of silymarin against bisphenol A-induced hepatotoxicity in mouse liver. Experimental and Therapeutic Medicine, 13(3), 821-828.

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Evaluating Cyclodextrin-based Liver Fibrosis Treatments

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All chemicals and solvents used in the study were of analytical grade.
2-Hydroxypropyl)-beta-cyclodextrin (HPBCD) and methyl-beta-cyclodextrin (RAMEB) were purchased from Cyclolab Ltd. (Budapest, Hungary). Silymarin 98% and carboxymethyl cellulose were purchased from Sigma-Aldrich (Germany). Rabbit polyclonal TGF-β1 (sc-146), rabbit polyclonal Smad 2/3 (sc-8332), mouse monoclonal α-SMA (sc-53142), rabbit polyclonal NF-κB p65 (sc-109) antibodies were supplied from Santa Cruz Biotechnology (Santa Cruz, CA, United States), rabbit polyclonal Anti-Col-I antibody (ab34710) from Abcam (United States) and mouse monoclonal Anti-MMP-1 antibody (NBP2-22123) from NovusBio (Novus, United States). Novocastra kit for immunohistochemistry was purchased from Leica Microsystems (Germany).

Gharbia S., Balta C., Herman H., Rosu M., Váradi J., Bácskay I., Vecsernyés M., Gyöngyösi S., Fenyvesi F., Voicu S.N., Stan M.S., Cristian R.E., Dinischiotu A, & Hermenean A. (2018). Enhancement of Silymarin Anti-fibrotic Effects by Complexation With Hydroxypropyl (HPBCD) and Randomly Methylated (RAMEB) β-Cyclodextrins in a Mouse Model of Liver Fibrosis. Frontiers in Pharmacology, 9, 883.

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