Rs 2000 biological cabinet x irradiator

Manufactured by Rad Source

The RS 2000 biological cabinet X-Irradiator is a piece of lab equipment designed for irradiation purposes. It features a cabinet enclosure and an X-ray source for controlled irradiation of samples.

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RS-2000 biological irradiator (50 citations) RS-2000 irradiator (30 citations)

2 protocols using rs 2000 biological cabinet x irradiator

X-Irradiation of Vestibular Schwannoma

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Radiation was delivered with an RS 2000 biological cabinet X-Irradiator (Rad Source Technologies). All cells were irradiated at room temperature (RT) and received a radiation dose of either 0 or 18 Gray (Gy) at 160kV and 25.0 mA, delivered at a dose rate of 1.85 Gy/min. The 18 Gy radiation dose was chosen because we wanted to analyze a supratherapeutic radiation dose for VS.

Thielhelm T.P., Goncalves S., Welford S., Mellon E.A., Bracho O., Estivil M., Brown C., Morcos J., Ivan M.E., Telischi F., Fernandez-Valle C, & Dinh C.T. (2021). Primary Vestibular Schwannoma Cells Activate p21 and RAD51-Associated DNA Repair Following Radiation-Induced DNA Damage. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 42(10), e1600-e1608.

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Dose-dependent human cell irradiation

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Primary human VS cells were irradiated at room temperature with a radiation dose of 0, 6, 12, or 18 Gy delivered by an RS 2000 biological cabinet X-Irradiator (Rad Source Technologies). Radiation was delivered at 1.85 Gy/min at 160 kV and 25.0 mA.

Thielhelm T.P., Nourbakhsh A., Welford S.M., Mellon E.A., Bracho O., Ivan M.E., Telischi F., Fernandez-Valle C, & Dinh C.T. (2022). RAD51 Inhibitor and Radiation Toxicity in Vestibular Schwannoma. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 167(5), 860-868.

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