Oxycon pro

Manufactured by Cardinal Health

Sourced in Germany, United States

The Oxycon Pro is a respiratory gas analysis system used to measure and monitor oxygen consumption, carbon dioxide production, and respiratory parameters in laboratory settings. It provides accurate and reliable data for evaluating cardiopulmonary function and exercise performance.

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Lab products found in correlation

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Spelling variants of this product

Jaeger Oxycon Pro (11 citations) Oxycon Pro/Delta (3 citations) Oxycon-Pro analyzer (2 citations)

24 protocols using oxycon pro

Measuring Maximal Oxygen Uptake

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The maximum oxygen uptake (

\dot{V} O 2

peak) was measured during the McMaster incremental cycle protocol with a breath-by-breath system (Oxycon Pro, Viasys Healthcare, Germany) calibrated prior to each test. Breath-by-breath data were averaged in 20 s intervals. For subjects ≥18 years old, predicted

\dot{V}

O₂ peak was calculated using equations published by Wasserman and Hansen [18 (link), 19 ], depending on age, sex, weight and height. For subjects < 18 years old the Cooper formula [19 , 20 (link)] was used to predict

\dot{V}

O₂ peak. An adjustment for overweight subjects was achieved with an addition of 6 mL.kg^− 1.min^− 1 for each kg of weight exceeding their normal weight [19 ] as calculated based on the 50th percentile of the World Health Organization body mass index charts for children [21 (link)].

Caru M., Petrykey K., Drouin S., Beaulieu P., St-Onge P., Lemay V., Bertout L., Laverdiere C., Andelfinger G., Krajinovic M., Sinnett D, & Curnier D. (2019). Identification of genetic association between cardiorespiratory fitness and the trainability genes in childhood acute lymphoblastic leukemia survivors. BMC Cancer, 19, 443.

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VO2 and VCO2 Monitoring During Exercise

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During each protocol VO₂ and VCO₂ were measured breath-breath via an online gas analysis system (Jaeger Oxycon Pro, Viasys Health Care, Warwick, UK). Heart rate (HR) was monitored continuously (Polar, Kempele, Finland).

Füssenich L.M., Boddy L.M., Green D.J., Graves L.E., Foweather L., Dagger R.M., McWhannell N., Henaghan J., Ridgers N.D., Stratton G, & Hopkins N.D. (2016). Physical activity guidelines and cardiovascular risk in children: a cross sectional analysis to determine whether 60 minutes is enough. BMC Public Health, 16, 67.

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Maximal Oxygen Uptake Protocol

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Subjects reported to the laboratory in the morning after an overnight fast. After 10 min of supine rest, subjects were scanned with whole‐body dual‐energy X‐ray absorptiometry (DXA). Thereafter, a graded exercise test was performed on a mechanically braked cycle‐ergometer to determine the maximum oxygen uptake (V˙O2max) and exercise capacity (incremental peak power output; (W). The test consisted of two 4‐min warm‐up bouts at a submaximal intensity. After 3 min of passive recovery, an incremental ramp test was performed starting at 80 W and with increments of 20 W min⁻¹ until volitional exhaustion. During the test, pulmonary gas exchanges were measured breath‐by‐breath using an online gas analysis system (Oxycon Pro, Viasys Healthcare, Hoechberg, Germany). V˙O2max was determined as the highest value achieved during a 30 s period. Criteria used for achievement of V˙O2max were a plateau in V˙O2 despite an increase in workload and a respiratory exchange ratio above 1.10.

Baasch‐Skytte T., Gunnarsson T.P., Fiorenza M, & Bangsbo J. (2021). Skeletal muscle proteins important for work capacity are altered with type 2 diabetes — Effect of 10‐20‐30 training. Physiological Reports, 9(1), e14681.

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Incremental Cycling to Exhaustion

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Prior to the experimental protocols, subjects performed an incremental cycle test to exhaustion. Testing was performed on a friction‐loaded cycle ergometer (839E; Monark Exercise AB, Varberg, Sweden) with pulmonary VO₂ measured by a breath‐by‐breath gas analyzing system (Oxycon Pro; Viasys Healthcare, Hoechberg, Germany) and heart rate (Polar Team² transmitter; Polar Electro Oy, Kempele, Finland) collected throughout the test. Prior to the experimental protocols, subjects also completed three familiarization sessions during which they performed speed endurance exercise (4, 6, and 6 × 30‐sec all‐out cycling separated by 3 min of active rest).

Skovgaard C., Brandt N., Pilegaard H, & Bangsbo J. (2016). Combined speed endurance and endurance exercise amplify the exercise‐induced PGC‐1α and PDK4 mRNA response in trained human muscle. Physiological Reports, 4(14), e12864.

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Maximal Oxygen Consumption Determination

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After a 3 h fast, participants performed an incremental exercise test to volitional exhaustion on an electromagnetically braked cycle ergometer (Lode Excalibur Sport, Groningen, The Netherlands) for the determination of maximum oxygen consumption (

\dot{V}

O_2max). Participants cycled at a self-selected pedal rate between 70 to 90 revolutions per minute for 3 min at 50 watts (warm up), followed by increments of 6 watts every 15 s until volitional fatigue. Expired air samples were monitored continuously using an online breath-by-breath gas analysis system (Oxycon Pro, Viasys Healthcare Gmbh, Höchberg, Germany). An average of the breath-by-breath

\dot{V}

O_2max data was calculated every 15 s, and

\dot{V}

O_2max was recorded as the highest 15 s average.

Benedetti S., Al-Tannak N.F., Alzharani M., Moir H.J., Stensel D.J., Thackray A.E., Naughton D.P., Dorak M.T., Spendiff O., Hill N., Watson D.G, & Allgrove J. (2019). Plasma Free Fatty Acids Metabolic Profile with LC-MS and Appetite-Related Hormones in South Asian and White European Men in Relation to Adiposity, Physical Activity and Cardiorespiratory Fitness: A Cross-Sectional Study. Metabolites, 9(4), 71.

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Incremental Cardiopulmonary Exercise Test

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Standard incremental cardiopulmonary exercise test until the symptom-limited maximum [16] (link) was performed on an electronically braked bicycle. The CPET protocol consisted in an unloaded pedalling during the first 3 minutes and then a ramp increment of load of 5 to10 watts/min for the patients, 20–30 watts for healthy subjects. Ventilation and gas analysis was performed by breathing through a mouthpiece throughout the test (Oxycon pro, Viasys Healthcare, Germany). Heart rate and blood pressure were obtained via automatic standard ECG and sphygmomanometer. Cardiac output measurements were obtained at rest, after the 3 minutes of unloaded pedalling and immediately after the completion of maximal exercise capacity (cardiac output measurements were obtained within 15–20 sec of the end of the test). The Innocor device and the volume transducer were mounted in series allowing measurements to be performed easily with the same mouthpiece.

Deboeck G., Taboada D., Hagan G., Treacy C., Page K., Sheares K., Naeije R, & Pepke-Zaba J. (2014). Maximal Cardiac Output Determines 6 Minutes Walking Distance in Pulmonary Hypertension. PLoS ONE, 9(3), e92324.

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Incremental Exercise Test for VO2peak

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An incremental exercise test was performed to determine VO_2peak. The test was conducted on the participants’ personal bikes, which were installed on a stationary Tacx-trainer device (Tacx Neo Smart T2800; Tacx, Netherlands). Following a 10 min warm up with 5 min at 100 W and 5 min at 175 W (80 RPM), workload was increased by 25 W/min until exhaustion. VO₂ and VCO₂ were obtained by breath-by-breath recordings (Jaeger Oxycon Pro; Viasys Healthcare, Germany). The gas analyzers and the flowmeter were calibrated before each test. A plateau in VO₂ despite increased workload and/or attainment of a respiratory exchange ratio (RER) ≥ 1.15 served as test validation criteria. VO_2peak was defined as the highest observed value over a 30s-period.

Oberholzer L., Siebenmann C., Mikkelsen C.J., Junge N., Piil J.F., Morris N.B., Goetze J.P., Meinild Lundby A.K., Nybo L, & Lundby C. (2019). Hematological Adaptations to Prolonged Heat Acclimation in Endurance-Trained Males. Frontiers in Physiology, 10, 1379.

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Symptom-limited Bicycle Ergometry Protocol

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All volunteers underwent symptom-limited exercise testing until maximum exhaustion on an electromagnetically braked bicycle ergometer in an upright sitting position (Ergoselect 100, Ergoline, Germany), using the modified Jones protocol: 3 min measurements at rest, 1 min unloaded cycling, stepwise increase of workload by 16 W/min, and 5 min recovery. Gas exchange and ventilation were measured breath by breath using an Oxycon Pro® system (VIASYS Healthcare GmbH, Hoechberg, Germany) with a CPET (7450 V2) mask. Calibration was performed before every exercise test [28 ].

Kaczmarek S., Habedank D., Obst A., Dörr M., Völzke H., Gläser S, & Ewert R. (2019). Interobserver variability of ventilatory anaerobic threshold in asymptomatic volunteers. Multidisciplinary Respiratory Medicine, 14, 20.

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Resting Energy Expenditure Assessment

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Resting energy expenditure (REE) was assessed with indirect computerized calorimetry (Oxycon Pro, VIASYS Healthcare^®, USA-Yorba Linda, CA, USA) during the morning after overnight fasting in patients who avoided smoking at least 24 h before the evaluation. The REE value (i.e., basal metabolic rate parameter) is necessary to set up the diet plan to induce an energy deficit of ~15% of daily requirements and was calculated using the Weir equation [kcal/d = 1.44 ∗ (3.94 ∗ VO₂ + 1.11 ∗ VCO₂)].

Brunani A., Cancello R., Gobbi M., Lucchetti E., Di Guglielmo G., Maestrini S., Cattaldo S., Piterà P., Ruocco C., Milesi A., Valerio A., Capodaglio P, & Nisoli E. (2023). Comparison of Protein- or Amino Acid-Based Supplements in the Rehabilitation of Men with Severe Obesity: A Randomized Controlled Pilot Study. Journal of Clinical Medicine, 12(13), 4257.

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Maximal Exercise Cardiorespiratory Assessment

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Measurements took place at baseline five to six weeks postoperatively, at the end of the 12‐week intervention and one year hereafter. On each occasion, current medication, body weight, height and blood pressure at rest were recorded and a venous blood sample was drawn for analysis of haemoglobin (Hb) concentration.
During a maximal exercise test on a cycle ergometer (eBike Basic, GE Medical Systems, GmbH, Freiburg, Germany), gas exchange and ventilatory variables were analysed (Jaeger Oxycon Pro, Viasys Healthcare, Hoechberg, Germany). The system was calibrated prior to each test. In addition, patients were monitored with ECG (Marquette CASE 8000, GE Medical Systems, Milwaukee, WI, USA), systolic blood pressure, rated perceived exertion (Borg RPE scale), chest pain and dyspnoea (Borg CR‐10 scale) (Borg, 1982).
After a five‐minute steady state workload at 30, 50 or 100 Watts, the workload was increased continuously by 10, 15 or 20 Watts per minute. The steady state and incremental loads were chosen individually at baseline, aiming to reach exhaustion after 8 to 12 min of exercise, and were used consistently throughout the study. Each CPET was driven as far as possible, pursuing the oxygen uptake levelling off and a respiratory exchange ratio above 1·10.

Nilsson H., Nylander E., Borg S., Tamás É, & Hedman K. (2018). Cardiopulmonary exercise testing for evaluation of a randomized exercise training intervention following aortic valve replacement. Clinical Physiology and Functional Imaging, 39(1), 103-110.

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