3.0 t trio tim mr system

The MRI scanning was performed on a Siemens 3.0 T Trio Tim MR system at the Shanghai Key Laboratory of Magnetic Resonance (East China Normal University, Shanghai, China). We used a 12-channel head coil for the whole brain scanning. Anatomical images were collected using a high-resolution T1-weighted 3-dimensional magnetization-prepared rapid-acquisition gradient-echo pulse sequence with the following acquisition parameters: repetition time (TR) = 2530 ms, echo time (TE) = 2.34 ms, flip angle = 7°, inversion time = 1100 ms, acquisition matrix = 256 × 256 mm², field of view (FOV) = 256 mm, 192 slices. A T2*-weighted gradient-echo echo-planar-imaging sequence, which is sensitive to blood oxygen level-dependent contrast, was used to collect functional images, with the following parameters: TR = 2000 ms, TE = 30 ms, FOV = 220 × 220 mm², acquisition matrix = 64 × 64, 33 slices, slice thickness = 3.5 mm, 25% gap. During the resting-state fMRI scan, we acquired 210 whole-brain volumes with the following parameters: TR = 2000 ms, TE = 30 ms, flip angle = 90°, slices = 33, transverse orientation, FOV = 220 × 220 mm², matrix size = 64 × 64, slice thickness = 3.5 mm, and 25% distance factor. All subjects were instructed to rest, relax, and not think of anything, with their eyes closed.