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Ecgonine

Manufactured by Merck Group
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Sourced in Sao Tome and Principe

Ecgonine is a chemical compound that serves as a precursor in the synthesis of cocaine. It is a white crystalline solid with the chemical formula C9H15NO3. Ecgonine is primarily used as an intermediate in the production of various pharmaceutical and illicit substances.

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Lab products found in correlation

Glutathione agarose, by Merck Group (2 mentions) Benzocaine, by Cayman Chemical (2 mentions) Benzoylecgonine, by Cayman Chemical (2 mentions) Benztropine, by Cayman Chemical (2 mentions) Procaine, by Cayman Chemical (2 mentions) Tropine, by Cayman Chemical (2 mentions) Neurobasal a medium, by Thermo Fisher Scientific (2 mentions) Benztropine, by Merck Group (2 mentions) Lidocaine, by Merck Group (2 mentions) Scopolamine, by Merck Group (2 mentions) 3h cocaine, by PerkinElmer (2 mentions) B 27 supplement minus antioxidants, by Thermo Fisher Scientific (2 mentions) Anisodamine, by Cayman Chemical (2 mentions) 3 p fbt hydrochloride, by Cayman Chemical (2 mentions) Cocaine hydrochloride, by Merck Group (2 mentions) Protein a g plus agarose, by Santa Cruz Biotechnology (2 mentions) B27 supplement, by Thermo Fisher Scientific (2 mentions) Benzoic acid, by Merck Group (2 mentions)

2 protocols using ecgonine

1

Dopamine Transporter Binding Assay

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Neurobasal-A medium (no glucose, no sodium pyruvate), B-27 supplement, and B-27 supplement minus antioxidants were purchased from Life Technologies. Cocaine hydrochloride, atropine, benzoic acid, benztropine, ecgonine, lidocaine, scopolamine, and glutathione agarose were purchased from Sigma-Aldrich. Anisodamine, benzocaine, benzoylecgonine, benztropine, 3-p-FBT (hydrochloride), procaine, and tropine were purchased from Cayman Chemical. Protein A/G PLUS-agarose was purchased from Santa Cruz Biotechnology. [3H]cocaine was purchased from PerkinElmer Life Sciences. FLAG-DAT plasmid (pcihygroflagsynhDAT) was a gift from Jonathan Javitch, Columbia University, New York, NY (Addgene plasmid #19990) (77 (link)). PDGF-TMD-GFP plasmid (pFU-no toxin-PE) was a gift from Ines Ibañez-Tallon, Rockefeller University, New York, NY (Addgene plasmid #24149) (78 (link)).
Harraz M.M., Malla A.P., Semenza E.R., Shishikura M., Singh M., Hwang Y., Kang I.G., Song Y.J., Snowman A.M., Cortés P., Karuppagounder S.S., Dawson T.M., Dawson V.L, & Snyder S.H. (2022). A high-affinity cocaine binding site associated with the brain acid soluble protein 1. Proceedings of the National Academy of Sciences of the United States of America, 119(16), e2200545119.
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2

Neuronal Cell Culture Reagents

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Neurobasal-A medium (no glucose, no sodium pyruvate), B-27 supplement and B-27 supplement minus antioxidants were purchased from Life Technologies (Grand Island, NY). Cocaine hydrochloride, atropine, benzoic acid, benztropine, ecgonine, lidocaine, scopolamine and glutathione agarose were purchased from Sigma-Aldrich (St. Louis, MO). Anisodamine, benzocaine, benzoylecgonine, benztropine, 3-p-FBT (hydrochloride), procaine, and tropine were purchased from Cayman Chemical (Ann Arbor, Michigan). Protein A/G plus-agarose was purchased from Santa Cruz Biotechnology (Paso Robles, CA). [ 3 H]cocaine was purchased from PerkinElmer Life Sciences (Boston, MA). FLAG-DAT plasmid (pcihygroflagsynhDAT) was a gift from Jonathan Javitch, Columbia University (Addgene plasmid # 19990) 28 . PDGF-TMD-GFP plasmid (pFU-no toxin-PE) was a gift from Ines Ibanez-Tallon (Addgene plasmid # 24149) 29 .
Harraz M.M., Malla A.P., Semenza E.R., Shishikura M., Hwang Y., Kang I.G., Song Y.J., Snowman A.M., Cortés P., & Snyder S.H. (2020). Cocaine receptor identified as BASP1.
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