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Tetrahydrofuran

Manufactured by Maclin Biochemical Technology
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Sourced in China

Tetrahydrofuran is a colorless, volatile, and flammable organic solvent. It is commonly used as a reagent and an intermediate in the production of various chemical compounds.

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Lab products found in correlation

Hydrochloric acid (hcl), by Maclin Biochemical Technology (10 mentions) Dimethyl sulfoxide (dmso), by Maclin Biochemical Technology (10 mentions) Sodium hydroxide (naoh), by Maclin Biochemical Technology (10 mentions) Dopamine hydrochloride, by Maclin Biochemical Technology (10 mentions) Ethylene glycol, by Xilong (3 mentions) Fecl3 6h2o, by Xilong (3 mentions) Tetracosanol, by Merck Group (3 mentions) Hexacosanol, by Merck Group (3 mentions) Octacosanol, by Merck Group (3 mentions) Triacontanol, by Merck Group (3 mentions) Malondialdehyde, by Nanjing Jiancheng (3 mentions) Tris buffer, by Sangon (3 mentions) 9 10 anthracenediyl bis methylene dimalonic acid, by Merck Group (3 mentions) Bovine serum albumin (bsa), by Merck Group (3 mentions) Ethylenediamine, by Maclin Biochemical Technology (2 mentions) Triethylamine, by Maclin Biochemical Technology (2 mentions) Benzimidazole bim, by Sinopharm (1 mentions) Chitosan, by Sinopharm (1 mentions) Sodium chloride (nacl), by Sinopharm (1 mentions) Nα cbz nim dnp l histidine, by GL Biochem (1 mentions)

15 protocols using tetrahydrofuran

1

Extraction and Purification of E. pela Wax

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E. pela wax—semifinished, first grade—was purchased from the Emeishan Institute of Insect Wax in Sichuan Province, southwestern China.
Sodium hydroxide, hydrochloric acid, chloroform, tetrahydrofuran, and lithium aluminum hydride (analytical grade) were supplied by Shanghai Maclean Biochemical Technology Co., Ltd. (Shanghai, China) A total of four PC standards, tetracosanol, hexacosanol, octacosanol, and triacontanol, were obtained from Sigma-Aldrich (Burlington, MA, USA) with a purity of >98%. Scopolamine hydrobromide was acquired from APExBIO (Houston, TX, USA) and dissolved in sterile normal saline at a final concen-tration of 4 mg/kg. Donepezil was purchased from the American MCE Company (Kowloon, Hongkong) and dissolved in 0.9% sterile normal saline at a final concentra-tion of 3 mg/kg. Sodium carboxymethyl cellulose (CMC-Na) was purchased from Bei-jing Soleibao Technology Co., Ltd. (Beijing, China). Assay kits for the determination of acetylcholine (Ach), acetylcholinesterase (AChE), superoxide dismutase (SOD), malondialdehyde (MDA), and glutathione (GSH) were purchased from Nanjing Jiancheng Institute of Biological Engineering (Nanjing, China). Normal saline (0.9%) was obtained from Hebei Tiancheng Pharmaceutical Co. Ltd. (Cangzhou, China).
Sun L., Li X., Ma C., He Z., Zhang X., Wang C., Zhao M., Gan J, & Feng Y. (2022). Improving Effect of the Policosanol from Ericerus pela Wax on Learning and Memory Impairment Caused by Scopolamine in Mice. Foods, 11(14), 2095.
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2

Synthesis and Characterization of Ce6-ABDA Conjugate

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Bovine Serum Albumin (BSA) and 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABDA) were purchased from Sigma Aldrich Co., Ltd. Ce6, dopamine hydrochloride, tetrahydrofuran (THF), and dimethyl sulfoxide (DMSO) were supplied by Shanghai Maclin Biochemical Technology Co., Ltd. Tris-buffer was purchased from Shanghai Sangon Biotech Co., Ltd. All chemicals were used without further purification.
Chen S., Jiang Y., Fan M., Zhang X., Zhang Y., Chen T., Yang C., Law W.C., Xu Z, & Xu G. (2022). Highly biocompatible chlorin e6-poly(dopamine) core–shell nanoparticles for enhanced cancer phototherapy. Nanoscale Advances, 4(21), 4617-4627.
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3

Ionophore-Based Electrochemical Sensors

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Sodium ionophore
(4-tert-butylcalix[4]arene), potassium ionophore
(valinomycin), calcium ionophore ETH-129 (C28H48N2O3), nitrite ionophore (C36H46CoN2O2), PMCB, POT, poly(vinyl chloride)
(PVC), tetrahydrofuran (THF), bis(2-ethylhexyl) sebacic acid (DOS),
sodium tetra[3,5-bis(trifluoromethyl)phenyl]borate (NaTFPB), dimethylformamide
hydroxymethyl (EDOT), decafluorooctanyl chloride, dichloromethane
(CH2Cl2), sodium bicarbonate (NaHCO3), and hexane were purchased from McLean Biochemical Technology Co.,
Ltd. (Shanghai, China). Deionized water with a resistivity of 18.2
mΩ·cm was prepared by the Pall Cascada Laboratory water
purification system. Other chemicals used were of analytical grade.
The four-channel screen-printed electrode (4w110) was purchased
from Metrohm AG. The electrode was composed of four working carbon
electrodes (2.95 mm diameter), which shared the auxiliary (carbon)
and reference (silver) electrodes.
Bao H., Ye J, & Zhang Y. (2024). A Multichannel Screen-Printed Carbon Electrode Based on Fluorinated Poly(3-octylthiophene-2,5-diyl) and Purified Mesoporous Carbon Black Simultaneously Detects Na+, K+, Ca2+, and NO2–. ACS Omega, 9(16), 18238-18248.
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4

Multifunctional PLGA Nanoparticles for Theranostics

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PLGA (Mw = 20 kDa, LA:GA = 50:50 mol/mol) was purchased from Jinan Daigang Biotechnology Co., Ltd. (Jinan, China). Tetrahydrofuran (THF, ≥99.0%) was bought from Macklin Biochemical Technology Co., Ltd. (Shanghai, China). FeCl3·6H2O (≥99.0%), ethylene glycol, and anhydrous sodium acetate (CH3COONa, NaAc) were provided by Xilong Science Co., Ltd. (Shantou, China). Y(NO3)3·6H2O (99.0%), polyethyleneimine (PEI), and NaBF4 were supplied by Shandong Xiya Chemical Industry Co., Ltd. (Linyi, China). Eu(NO3)3·6H2O (99.99%) and DOX (≥98.0%) were bought from Aladdin Industrial Corporation (Shanghai, China). NaCl, chitosan (CS, degree of deacetylation: 80–95%, viscosity: 0.05–0.8 Pa·s), and benzimidazole (Bim) were provided by Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Diethylene glycol (DEG) was acquired from the Tianjin Guangfu Fine Chemicals Institute (Tianjin, China). Acetic acid (CH3COOH, AcOH) was received from Tongguang Fine Chemicals Company (Beijing, China). Absolute ethyl alcohol (≥99.7%) was purchased from Beijing Oriental Technology Development Co., Ltd. (Beijing, China). Deionized water was used in all experiments. All reagents involved in this work were of analytical grade and directly used as received without further purification.
Xu J., Jia Y., Liu M., Gu X., Li P, & Fan Y. (2021). Preparation of Magnetic–Luminescent Bifunctional Rapeseed Pod-Like Drug Delivery System for Sequential Release of Dual Drugs. Pharmaceutics, 13(8), 1116.
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5

Synthesis and Characterization of HA-Based Nanoparticles

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HA (Mw = 10,000), thionyl chloride, tetrahydrofuran, isopropylamine, N, N-Dimethylformamide (DMF), N, N′-Carbonyldiimidazole (CDI), ethylenediamine and FA were obtained from Macklin Biochemical Co., Ltd. (Shanghai, China). Nα-CBZ-Nim-DNP-L-histidine, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), N-Hydroxysuccinimide (NHS) and N, N′-Dicyclohexylcarbodiimide (DCC) were obtained from GL Biochem Ltd. (Shanghai, China). PF127 was obtained from the BASF (Shanghai, China). DTX was obtained from the Jinhe Biotechnology Co., Ltd. (Shanghai, China). 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl tetrazolium bromide (MTT), coumarin 6 (Cou-6) and 4′,6-diamidino-2-phenylindole (DAPI) were obtained from Sigma (St. Louis, MO, USA).
Yang D., Li Z., Zhang Y., Chen X., Liu M, & Yang C. (2023). Design of Dual-Targeted pH-Sensitive Hybrid Polymer Micelles for Breast Cancer Treatment: Three Birds with One Stone. Pharmaceutics, 15(6), 1580.
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6

Synthesis and Characterization of NIPAM-Based Hydrogels

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N-isopropylacrylamide (NIPAm, 97%, M.W. 113.16 g/mol) was purchased from Sigma‒Aldrich, and 2-methacryloyloxyethyl-trimethyl ammonium chloride (DMC), 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), azoisobutyronitrile (AIBN), tetrahydrofuran (THF), dipotassium phosphate (K2HPO4), calcium chloride dihydrate (CaCl2·2H2O), sodium hydroxide (NaOH), sodium chloride (NaCl), ethanol and ammonia were all obtained from Shanghai Macklin Biochemical Technology Co., Ltd. Poly-γ-glutamic acid (γ-PGA, Mw=2000 kDa) was purchased from Yuanye Biotechnology Co., Ltd. (Shanghai, China). All chemicals were used as received without further purification.
Yuan R., Zhang Y., Liao L., Ge Y., Li W, & Zhi Q. (2023). Biomineralization-Inspired Anti-Caries Strategy Based on Multifunctional Nanogels as Mineral Feedstock Carriers. International Journal of Nanomedicine, 18, 4933-4947.
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7

Catalytic Conversion of Furans

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The following chemicals were utilized as provided without further purification: Co(NO3)2·6H2O (99%, Sinopharm Chemical Reagent Co., Ltd., Beijing, China), NaOH (≥98%, Shanghai Aladdin Bio-Chem Technology Co., Ltd., Shanghai, China), 5-hydroxymethylfurfural (HMF, 98%, Shanghai Bide Pharmatech Co., Ltd., Shanghai, China), 2,5-dimethylfuran (DMF, 99%, Shanghai Energy Chemical Co., Ltd., Shanghai, China), tetrahydrofuran (THF, 99%, Shanghai Macklin Biochemical Co., Ltd., Shanghai, China), 2,5-bis(hydroxymethyl)furan (BHMF, 98%, Shanghai Macklin Biochemical Co., Ltd., Shanghai, China), 2-methyl-5-hydro-xymethylfuran (MFA, 99%, Shanghai Sigma-Aldrich Co., Ltd., Shanghai, China), Cinnamyl aldehyde (98%, Shanghai Macklin Biochemical Co., Ltd., Shanghai, China), Acetophenone (≥98%, Shanghai Macklin Biochemical Co., Ltd., Shanghai, China), Styrene (99%, Shanghai Macklin Biochemical Co., Ltd., Shanghai, China), and Phenol (≥99.5%, Shanghai Aladdin Bio-Chem Technology Co., Ltd., Shanghai, China).
Yang K., Chen N., Guo X., Zhang R., Sheng X., Ge H., Zhu Z., Yang H, & Lü H. (2023). Phase-Controlled Cobalt Catalyst Boosting Hydrogenation of 5-Hydroxymethylfurfural to 2,5-Dimethylfuran. Molecules, 28(13), 4918.
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8

Synthesis and Characterization of Gold Nanoparticles

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Gold (III) chloride trihydrate (HAuCl4·3H2O, ≥99.9%), hexadecyltrimethylammonium bromide (CTAB), cetyltrimethylammonium chloride solution (CTAC, 25 wt% in H2O), and L-ascorbic acid (AA, ≥99%) were purchased from Sigma Aldrich. Sodium Oleate (NaOL, 98%), sodium borohydride (NaBH4, ≥99%), silver nitrate (AgNO3, 99.99%), Hydrochloric Acid (HCl, 37 wt% in H2O), Tetrahydrofuran (THF, 99%) and Chloroform (99%) were obtained from MACKLIN. Thiol-functionalized polystyrene (Mn = 50,000 g mol−1, Mw/Mn= 1.06) was obtained from Polymer Source Inc. Bovine serum albumin (BSA, Fraction V) was obtained from Solarbio. Quantifoil holey carbon films (400 mesh with 37 μm × 37 μm square holes) and Gilder Square Grids (2,000 mesh with 7.5 × 5 μm2 and 300 mesh with 54 × 54 μm2 square holes) were purchased from Zhongjingkeyi Technology Co., Ltd.
All chemicals were used as-received unless otherwise indicated. Demineralized water was used in all aqueous solutions, which were further purified with a Milli-Q system (Millipore). All glassware used in the following procedures were cleaned in a bath of freshly prepared aqua regia and were rinsed thoroughly in H2O prior to use.
Chen Y., Liu H., Yin H., Zhu Q., Yao G, & Gu N. (2020). Hierarchical Fabrication of Plasmonic Superlattice Membrane by Aspect-Ratio Controllable Nanobricks for Label-Free Protein Detection. Frontiers in Chemistry, 8, 307.
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9

Synthesis of DOX-Loaded Gold Nanoparticles

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All glassware and stirring magnets were washed with aqua regia (HCl : HNO3 volume ratio = 3 : 1) and rinsed with ultrapure water thoroughly. Gold(iii) chloride trihydrate (HAuCl4·3H2O, Macklin, China), bovine serum albumin (BSA, Macklin, China), sodium hydroxide (NaOH, Macklin, China), ethanol (Macklin, China), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC, Macklin, China), ethylenediamine (EDA, Macklin, China), doxorubicin hydrochloride (DOX·HCl, Macklin, China), triethylamine (TEA, Macklin, China), dimethyl sulfoxide (DMSO, Macklin, China) and tetrahydrofuran (THF, Macklin, China) were used as received.
Yang J., Zhang L., Zhou Q., Chen F., Stenzel M., Gao F., Liu C., Yuan H., Li H, & Jiang Y. (2021). Self-assembled anionic and cationic Au nanoparticles with Au nanoclusters for the exploration of different biological responsiveness in cancer therapy. Nanoscale Advances, 3(10), 2812-2821.
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10

Synthesis and Characterization of Quaternized Silicones

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1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP, 99.5%), N-isopropylacrylamide (NIPAm, 98%), 2,2′-Azobis(2-methylpropionitrile) (98%), and Tetrahydrofuran (AR, 99.0%) were supplied by Shanghai Macklin Biochemical Co., Ltd. (China). Octadecyl acrylate (SA, ≥97%), N-(Hydroxymethyl) acrylamide (NMA, ≥98%) were purchased from Shanghai Haohong Biotechnology Co., Ltd. (China). Penicillin-Streptomycin Liquid (100 ×) and Trypsin-EDTA solution were provided by Beijing Solarbio Science and Technology Co., Ltd. (China). Phosphate Buffer Saline (PBS) and powder (7.2–7.4) were provided by Servicebio Biotech, Co., Ltd. (China). Polycaprolactone Standard (PCL, MW 80000) was from Shenzhen Esun Industrial Co., Ltd. (China). DMEM (high glucose) were obtained from Cytiva Co., Ltd. (American). The group synthesized quaternized silicones (QP12) by silica-hydrogen addition reaction of polymethylhydrosiloxane in the early stage.
Qi Q., Li R., Wang C., Hou G, & Li C. (2023). Embryonic perfect repair inspired electrospun nanofibers dressing with temperature-sensitive and antibacterial properties for wound healing. Frontiers in Microbiology, 14, 1233559.
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