C57bl 6j wild type 000664

All the procedures involving animal use were in compliance with the policies of the Institutional Animal Care and Use Committee (IACUC) at Boston University (protocol #: 14-033). C57BL/6J wild-type (#000664) and SIRT2 knock-out mice (B6.129-Sirt2^tm1.1Fwa/J, #012772) were obtained from Jackson Laboratory (Bar Harbor, ME). Mouse colonies were maintained in the Laboratory Animal Care Facility (LACF) at Boston University, Charles River Campus. The mice aged 8–15 weeks of either sex were randomly selected from different litters. Only mice with normal body size, morphology and no observable disabilities were used for the experiments.

All animal experiments were approved by the Institutional Animal Care and Use Committees of the Emory University and Yonsei University College of Medicine, and were performed in accordance with federal guidelines. C57BL/6J wild-type (#000664) or transgenic mice carrying a GFP reporter driven by human ubiquitin C (UBC-GFP, #004353) promoters or an mCherry reporter driven by the MYH6 promoter (MYH6-mCherry, #021577) were purchased from Jackson Laboratory. Nkx2–5-GFP transgenic mice were kindly given by Dr. Richard P. Harvey (Victor Chang Cardiac Research Institute)^{56 (link)}.