Included patients were those who visited a specialized corneal clinic at University Tokyo Hospital and underwent corneal tomographic analysis for scarring after infectious keratitis caused by bacteria, fungi, herpesvirus, and acanthamoeba between January 2014 and May 2021. We excluded patients who developed a corneal infection after transplantation, underwent therapeutic corneal transplantation, and had another corneal disease or a history of corneal surgery. Corneal tomographic analysis was performed using AS-OCT (CASIA or CASIA2; Tomey Corporation, Inc., Aichi, Japan) within 1 year after complete recovery from abscess without any corneal epithelial defects.
Casia
Manufactured by Tomey
Sourced in Japan
The CASIA is a high-performance optical coherence tomography (OCT) system designed for clinical and research applications. It provides detailed, non-invasive imaging of the anterior and posterior segments of the eye.
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Lab products found in correlation
Casia2, by Tomey (2 mentions)
Em 3000, by Tomey (1 mentions)
Ark 1, by Nidek (1 mentions)
Nt 530, by Nidek (1 mentions)
Iolmaster 500, by Zeiss (1 mentions)
Oa 2000, by Tomey (1 mentions)
Cirrus hd oct, by Zeiss (1 mentions)
Dri oct triton, by Topcon (1 mentions)
Lenstar, by Haag-Streit (1 mentions)
12 protocols using casia
1
Corneal Scarring After Infectious Keratitis
2
Evaluating Bleb Characteristics Post-Glaucoma Surgery
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A photo was taken of each bleb with a digital camera (CX4; RICOH, Tokyo, Japan), and its area and vascularity at 1, 2, 4, and 12 weeks postoperatively were classified using the Moorfields Bleb Grading System (http://blebs.net/ ) by three independent researchers who were blind to the condition of the bleb (n = 3, each).
Anterior-segment OCT images were acquired using CASIA® (Tomey, Nagoya, Japan) 2, 5, 7, and 14 days postoperatively (n = 3, each), and the intensity of the bleb wall in the horizontal image was measured using CASIA bleb assessment software ver. 4.0L (Tomey).
Anterior-segment OCT images were acquired using CASIA® (Tomey, Nagoya, Japan) 2, 5, 7, and 14 days postoperatively (n = 3, each), and the intensity of the bleb wall in the horizontal image was measured using CASIA bleb assessment software ver. 4.0L (Tomey).
3
Retrospective Study of DALK in Keratoconus
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In this institutional retrospective cohort study, the records of all consecutive DALK procedures performed in patients affected by KC at a tertiary referral Center (Department of Ophthalmology, University of Magna Graecia, Catanzaro, Italy) from September 2014 to February 2019 were reviewed. The study followed the tenets of the 2013 Declaration of Helsinki and was approved by the local Ethics Committee (Comitato Etico Università Magna Graecia of Catanzaro, Italy). Informed consent was obtained from all patients undergoing surgery. Patients who did not gain useful visual acuity with spectacles and were contact lens were considered candidates for surgery. Eyes with previous hydrops or evident lesions of DM were excluded. Preoperatively, all patients underwent a complete ophthalmologic evaluation including slit-lamp examination, corrected distance visual acuity (CDVA) expressed both in logarithmic units of the minimum angle of resolution (logMAR) and in Snellen fraction, refraction, tonometry, fundoscopy, endothelial specular microscopy (EM-3000; Tomey, Erlangen, Germany), and anterior segment optical coherence tomography (AS-OCT) (Casia; Tomey, Tokyo, Japan).
4
Comprehensive Ocular Evaluation for Cataract Surgery
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All patients in this study underwent comprehensive ocular examinations, including best-corrected visual acuity (BCVA) measurement, IOP measurement with noncontact tonometry (Nidek NT-530, Gamagori, Japan), K measurement with an ophthalmokeratometer (Topcon KR-8100A, Tokyo, Japan or Nidek ARK-1, Gamagori, Japan), CCT measurement with a CASIA (Tomey, Nagoya, Japan), ACD measurement with a CASIA, AL measurement with an IOL Master 500 (Carl Zeiss Meditec, Germany) or OA2000 (Tomey, Nagoya, Japan), and slit-lamp biomicroscopy. The IOL power was calculated using the SRK/T, Barrett Universal II (Barrett), Hill-Radial Basis Function (RBF) 3.0, and Kane formula. We measured AL in the phakic mode preoperatively and in the pseudophakic mode postoperatively. Patients were followed up at more than 1 month after phacoemulsification.
5
Post-Surgery Graft Monitoring and Management
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After surgery, a pressure patch was applied and patients were instructed to lie on their backs for 2 hours before being checked at the slit lamp. If a pupillary block was present, a small amount of air was released from the main wound. Beginning the next morning, the postoperative medical treatment followed the regimen described in detail previously.15 Two to 3 hours after surgery, as well as 1 day postoperatively, each eye was examined by means of a photographic slit-lamp to measure the air level in the anterior chamber and digital pictures were taken to document the data collected.
According to the amount of air in the anterior chamber, eyes were assigned to one of 3 sub-groups (air levels of 75%, 50%, and 25%), as shown in figure 1 left, center and right, respectively. Anterior segment optical coherence tomography (AS-OCT) (CASIA, Tomey, Tokio, Japan) was also performed in each eye in order to detect any detached part of the graft. Re-bubbling was performed in all cases of graft detachment, as documented by means of AS-OCT, regardless of the extension of the detached area.
According to the amount of air in the anterior chamber, eyes were assigned to one of 3 sub-groups (air levels of 75%, 50%, and 25%), as shown in figure 1 left, center and right, respectively. Anterior segment optical coherence tomography (AS-OCT) (CASIA, Tomey, Tokio, Japan) was also performed in each eye in order to detect any detached part of the graft. Re-bubbling was performed in all cases of graft detachment, as documented by means of AS-OCT, regardless of the extension of the detached area.
6
Corneal Changes and IOP Measurement
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The central corneal thickness (CCT) and corneal meridians, which may influence IOP measurement, were measured with anterior-segment optical coherence tomography before and after 24 h IOP measurement in each eye. The CCT, steeper meridian, and flatter meridian of all patients were measured twice before and after the surgeries with CASIA (Tomey Corp. Nagoya, Japan). We compared the differences before and after surgeries, and before and after the measurement of CLS. If there is a significant difference in the corneal curvature before and after the surgery, it will affect the data with CLS, so it is necessary to confirm.
7
Optimal ICL Selection for Optimal Vault
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The appropriate ICL crystal size is selected based on STAAR online calculation and clinical experience, and all eye surgeries are performed by the same experienced surgeon. Recording of vault measured by a high-resolution anterior segment optical coherence tomography (AS-OCT, CASIA, Tomey Corporation, Aichi, Japan) at 1 month postoperatively.
8
Pupil-sparing Multimodal Imaging for Glaucoma
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Our prototype SLO, along with optical coherence tomography (OCT) and fundus photography, was used without pupil dilation. The OCT devices used were spectraldomain OCT (Cirrus HD-OCT, Carl Zeiss Meditec, Inc., Dublin, USA) or swept-source OCT (DRI OCT Triton, Topcon, Inc., Tokyo, Japan). Among the 55 patients, 14 had their pupil diameters previously measured clinically with anterior segment OCT (CASIA or CASIA2, Tomey Corporation, Nagoya, Japan), and all 14 were glaucoma patients.
9
Preoperative and Postoperative Corneal Assessments
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In addition to standard examinations performed using slit-lamp microscopy, the following factors were evaluated preoperatively and at 1, 3, 6, and 12 months postoperatively in all eyes: 1) topographic factors determined by anterior segment optical coherence tomography (AS-OCT; CASIA, Tomey, Nagoya, Japan); aberration factors (HOAs, spherical aberrations [SAs], and coma aberrations [Comas] at a 6.0-mm diameter in the anterior-, posterior-, and total cornea); keratometric values (KV of the anterior, posterior, and total cornea; diopter [D]); corneal thickness (central corneal thickness [CCT] and peripheral corneal thickness [PCT] at 9.0 mm); and best spectacle-corrected visual acuity (BCVA; logarithm of the minimal angle of resolution [logMAR]). Outcomes were compared with healthy controls.
10
Iris-Fixated Phakic Intraocular Lens Selection
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We determined the ICL size (12.1, 12.6, 13.2, and 13.7 mm) based on the KS prediction formula using AS-OCT (CASIA, Tomey Corporation, Aichi, Japan). We also selected the ICL power using an online calculation and ordering system provided by the manufacturer based on a modified vertex formula [11 (link), 12 (link)]. We chose the toric model ICL in eyes with manifest astigmatism of 1 D or more and the non-toric model ICL in eyes with less than 1 D.
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