Sn60at

Manufactured by Alcon

Sourced in United States

The SN60AT is a laboratory equipment product. It is designed to perform specific functions in a laboratory setting. The core function of the SN60AT is to provide controlled and consistent results for laboratory tasks, but a detailed description cannot be provided while maintaining an unbiased and factual approach.

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Lab products found in correlation

Sn60wf, by Alcon (3 mentions) Sa60at, by Alcon (2 mentions) Ma60ac, by Alcon (1 mentions) Iolmaster 500, by Zeiss (1 mentions) Acrysof sa60at, by Alcon (1 mentions) Ma60ac iols, by Alcon (1 mentions)

Spelling variants of this product

Acrysof SN60AT (14 citations) Acrysof SN60AT and MA60AC IOLs (2 citations)

6 protocols using sn60at

Randomized Cataract IOL Comparison

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Before the cataract surgery, the axial length of the eye will be measured with an A-scan UD-6000 (Tomey, Nagoya, Japan). Yellow aspherical IOL (SN60WF, Alcon, Fort Worth, Texas, United States), yellow spherical IOL (SN60AT, Alcon, Fort Worth, Texas, United States), or clear spherical IOL (SA60AT, Alcon, Fort Worth, Texas, United States) will be used for the cataract surgery. The appropriate power of the IOL will be estimated using the SRK/T formula for each IOL
[42 (link)]. The kind of IOL used for the cataract surgery was randomly allocated to yellow spherical IOL, yellow aspherical IOL, or clear spherical IOL in a 1:1:2 ratio. After phacoemulsification with a small incision, IOL will be implanted.

Saeki K., Obayashi K., Nishi T., Miyata K., Maruoka S., Ueda T., Okamoto M., Hasegawa T., Matsuura T., Tone N., Ogata N, & Kurumatani N. (2014). Short-term influence of cataract surgery on circadian biological rhythm and related health outcomes (CLOCK-IOL trial): study protocol for a randomized controlled trial. Trials, 15, 514.

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Biometric Measurements for Cataract Surgery

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Biometry was done under general anesthesia for all patients except 73 older patients who had preoperative outpatient optical biometry using a Zeiss IOLMaster^® 500 (Carl Zeiss, Meditec AG, Germany). K-readings were obtained using Righton Retinomax K-Plus 2 handheld autokeratometer (Nikon, Tokyo, Japan) taking the average of 3 readings which varied by <1 diopter (D). AL was obtained by applanation A-scan ultrasound (Sonomed Pac Scan Plus 300AP+, Sonomed Escalon, New York, USA) taking the average of at least five readings which varied by ≤0.09 standard deviation (SD). The A-constant provided by the manufacturer was used. SRK II formula was used for IOL power calculation and the power was determined according to the age and status of the fellow eye. All patients underwent cataract extraction using a similar technique and AcrySof biconvex hydrophobic acrylic, IOL models MA60AC, SA60AT and SN60AT (Alcon, Texas, USA) were implanted. Postoperative cycloplegic refraction was performed at the two-month follow-up visit either using a retinoscope by a senior pediatric ophthalmologist or an autorefractometer in cooperative older children.

Shuaib A.M., Elhusseiny A.M., Hassanein D.H., Zedan R.H, & Elhilali H.M. (2021). Predictive Value of Intraocular Lens Power Calculation Formulae in Children. Clinical Ophthalmology (Auckland, N.Z.), 15, 2527-2536.

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Rabbit Capsule Adhesion IOL Study

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The IOL used in this study was the sharp edge-designed SN60AT (Alcon, USA) with 30D power. Although the rabbit capsule was larger than the human capsule, the IOL with 13.0 mm haptic length and nice adhesion characteristics was used in this study to reduce the maximum extent of effects among different species.

Chang P., Lin L., Zheng Q., Yu F., Yu X., Zhao Y., Ding X., Zhu W., Li J, & Zhao Y.E. (2016). An Optical Section-Assisted In Vivo Rabbit Model for Capsular Bend and Posterior Capsule Opacification Investigation. PLoS ONE, 11(2), e0148553.

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Pediatric Cataract Surgery Outcomes

Cited 1 time

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All surgeries were performed by two experienced pediatric ophthalmologists (YZL and WRC). Anterior capsulotomy was performed in a continuous curve. The nucleus and cortex were removed using an irrigation/aspirating handpiece. Posterior capsulotomy and limited anterior vitrectomies were performed in children aged 6 years or younger (11 (link)). The axial length was measured preoperatively by contact A-scan ultrasound (B-SCAN-Vplus/BIOVISION, Quantel Medical, France), and the SRK-T formula was used to calculate the IOL power. The refractive targets were set with reference to the practice styles and preferences of the American Society of Cataract and Refractive Surgery (ASCRS) and the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) members, ranging from +6D to +1D according to the patient’s age (12 (link), 13 (link)). The AcrySof SA60AT, SN60AT, and MA60AC IOLs (Alcon Laboratories, Fort Worth, TX, USA) were implanted in the capsular bag.

Lin D., Zhu Q., Zhang S., Zhou F., Zhao L., Wang Q., Chen W., Chen H., Lin X., Feng H., Zhong Q., Chen J., Lin Z., Li X., Xiao W., Zhou Y., Wang J., Li J, & Chen W. (2024). Postoperative myopic shift and visual acuity rehabilitation in patients with bilateral congenital cataracts. Frontiers in Medicine, 11, 1406287.

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Trifocal IOL Visual Acuity Outcomes

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This study was designed to examine the non-inferiority in CDVA and superiority in distance-corrected near (at 40 cm, DCNVA) and intermediate (at 80 cm, DCIVA) visual acuities at 6 months postoperatively compared with monofocal IOLs. Based on the previous studies of SN60AT [5 (link)] and SN60WF [6 (link)] IOLs (Alcon, Fort Worth, USA), mean postoperative DCVA, DCNVA and DCIVA of − 0.039, 0.529 and 0.23 in logMAR value, respectively, were considered as historical control. Sixteen patients or more were required with detection power > 90%, significance level of 2.5% (one sided test) for non-inferiority with a margin of 0.10 logMAR and the superiority in the use of trifocal IOLs. The discontinuation of 30% of individual subjects was anticipated considering the influence of COVID-19 during the study period. Thus, the sample size was planned to be 22 patients or more.

Mori Y., Miyata K., Suzuki H., Noguchi S., Ichikawa K, & Maeda N. (2022). Clinical Performance of a Hydrophobic Acrylic Diffractive Trifocal Intraocular Lens in a Japanese Population. Ophthalmology and Therapy, 12(2), 867-878.

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Congenital EL Patients: IOL and MCTR

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A total of 367 patients with congenital EL were operated from June 2018 to April 2021 were screened for the study. Further selection was carried out considering data integrity, history of other ocular diseases, type of IOL, and MCTR.
Exclusion criteria: history of vision correction surgery, glaucoma, keratoconus, uveitis, or retinal detachment. Inclusion criteria: for the types of implanted IOL, the 3 most used ones (AcrySof SN60WF or SN60AT; Alcon; ZCB00; Tencis), possessing similar optical performance, were considered eligible. While the MCTR types were restricted to the 4 frequently used ones (1L, 1G, 2C, and 2S) that have equivalent mechanical properties. Finally, 91 eyes of 60 patients were included in this study. The selection process of the study cohort is summarized in Figure 1.

Chen T.H., Song L.H., Liu Y., Zhao Y., Chen Z.X, & Jiang Y.X. (2023). Comparison of Accuracy in Keratometries Measured by Different Camera Devices for Predicting the Intraocular Lens Power in Lens-Dislocated Patients. Ophthalmic research, 66(1).

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