Tested compounds (i.e. 8HQ and derivatives) and antibiotics are comercially available. 8-Hydroxyquinoline (8HQ, 1 ); 5-chloro-8-Hydroxyquinoline (5-Cl-8HQ or cloxyquin, 2 ); 5-nitro-8-Hydroxyquinoline (5-NO2-8HQ or nitroxoline, 3) ; 7-bromo-8-Hydroxyquinoline (7-Br-8HQ, 4 ); 5,7-diiodo-8-Hydroxyquinoline (5,7-diI-8HQ or iodoquinol, 5 ) and 5-chloro-7-iodo-8-hydroxy- quinoline (5-Cl-7-I-8HQ or clioquinol, 6 ) were obtained from Sigma-Aldrich. 5,7-Dichloro-8-Hydroxyquinoline (5,7-diCl-8HQ, 7 ) was purchased from Acros Organics. Spectinomycin was supplied with Bio Basic Inc. Chemical structures of the tested compounds are shown in Figure 1(Fig. 1) .
5 chloro 7 iodo 8 hydroxy quinoline
Manufactured by Merck Group
5-chloro-7-iodo-8-hydroxy-quinoline is a chemical compound. It is a pale yellow crystalline solid. The compound can be used as a building block in organic synthesis.
Automatically generated - may contain errors
2 protocols using 5 chloro 7 iodo 8 hydroxy quinoline
1
Antimicrobial Evaluation of 8HQ Derivatives
2
Synthesis and Purification of Quinoline Derivatives
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
8-Hydroxy-quinoline (54 ; cat.
no. 252565, 99% purity), 2-methyl-8-hydroxy-quinoline (55 ; cat. no. H57602, 98% purity), 5,7-dichloro-2-methyl-8-hydroxy-quinoline
(61 ; cat. no. 130532, 98% purity), and 5-chloro-7-iodo-2-methyl-8-hydroxy-quinoline
(59 ; cat. no. PH004692) were purchased from Sigma-Aldrich,
5-chloro-7-iodo-8-hydroxy-quinoline (58 ; cat. no. A11137,
98% purity) was purchased from Alfa Aesar, 5,7-dichloro-8-hydroxy-quinoline
(60 ; cat. no. 11343, 99% purity) was obtained from Acros
Organics. All ChemBridge compounds were certified to have met the
high quality standard of 100% NMR identification and had a purity
level of at least 90%. Purity of ChemDiv compounds was confirmed by
the supplier by LC/MS and NMR and had a purity of >95%. All synthesized
compounds assayed for enzyme activity were purified by semipreparative
reversed phase HPLC and found to be greater than 95% pure based on
analysis by 300 MHz 1H NMR and analytical scale reversed
phase HPLC with diode array detection.
no. 252565, 99% purity), 2-methyl-8-hydroxy-quinoline (
(
(
5-chloro-7-iodo-8-hydroxy-quinoline (
98% purity) was purchased from Alfa Aesar, 5,7-dichloro-8-hydroxy-quinoline
(
Organics. All ChemBridge compounds were certified to have met the
high quality standard of 100% NMR identification and had a purity
level of at least 90%. Purity of ChemDiv compounds was confirmed by
the supplier by LC/MS and NMR and had a purity of >95%. All synthesized
compounds assayed for enzyme activity were purified by semipreparative
reversed phase HPLC and found to be greater than 95% pure based on
analysis by 300 MHz 1H NMR and analytical scale reversed
phase HPLC with diode array detection.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!