Psd 95 shrna lentiviral particles

Manufactured by Santa Cruz Biotechnology

PSD-95 shRNA lentiviral particles are a tool used to knockdown expression of the PSD-95 (Postsynaptic Density Protein 95) gene. The particles contain shRNA (short hairpin RNA) designed to target and silence the PSD-95 gene. This product can be used for in vitro studies to investigate the role of PSD-95 in cellular processes.

Automatically generated - may contain errors

Lab products found in correlation

Control shrna lentiviral particles, by Santa Cruz Biotechnology (1 mentions) Picrotoxin, by Bio-Techne (1 mentions) D serine, by Bio-Techne (1 mentions) 2 bromopalmitate 2 bp, by Merck Group (1 mentions) Mk 801, by Bio-Techne (1 mentions) L 689 560, by Bio-Techne (1 mentions) Ly367385, by Bio-Techne (1 mentions)

2 protocols using psd 95 shrna lentiviral particles

Lentiviral Knockdown of PSD-95 in Cortical Neurons

Cited 1 time

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PSD-95 shRNA lentiviral particles (Santa Cruz Biotechnology) or control shRNA lentiviral particles [19 (link)] was added to primary cortical neurons at days in vitro (DIV) 7. After 7 days of growth in the presence of the shRNAs, neurons were treated with bicuculline or vehicle and harvested in RIPA buffer with phosphatase and protease inhibitors.

Xu J., Kurup P., Nairn A.C, & Lombroso P.J. (2017). Synaptic NMDA receptor activation induces ubiquitination and degradation of STEP61. Molecular neurobiology, 55(4), 3096-3111.

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Molecular Techniques for Cellular Studies

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All antibodies used in this study are listed in the Supplementary Table 1. Bicuculline, MG-132, LY294002 calpeptin, tetrodotoxin and glycine were obtained from Calbiochem (San Diego, CA). (+)-MK-801, CNQX, LY 367385, MPEP, L-689560, D-serine and picrotoxin were purchased from Tocris Biosciences (Ellisville, MO). 2-Bromopalmitate (2-BP) was purchased from Sigma-Aldrich (St. Louis, MO). PSD-95 shRNA lentiviral particles were purchased from Santa Cruz Biotechnology (Santa Cruz, CA).

Xu J., Kurup P., Nairn A.C, & Lombroso P.J. (2017). Synaptic NMDA receptor activation induces ubiquitination and degradation of STEP61. Molecular neurobiology, 55(4), 3096-3111.

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