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Fmoc osu

Manufactured by GL Biochem
Sourced in China

Fmoc-OSu is a chemical compound used in solid-phase peptide synthesis. It acts as a protecting group for the amino group of amino acids, allowing for the controlled and sequential addition of amino acids during the synthesis process. The core function of Fmoc-OSu is to facilitate the protection and deprotection of amino groups in peptide synthesis.

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2 protocols using fmoc osu

1

Synthesis of Bisethynyl-functionalized DBT

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Fmoc-OSu and other Fmoc-amino acids were purchased from GL Biochem (Shanghai, China). 2-Cl-trityl chloride resin (1.0–1.2 mmol g−1) was purchased from Nankai University Resin Co. Ltd. Human LAPTM4B full length protein was bought from Abcam. All the other starting materials were bought from Sigma-Aldrich. Chemical reagents and solvents were utilized as received from commercial sources. Bisethynyl-functionalized DBT was synthesized according to previous literature7 (link).
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2

Fmoc-Based Peptide Synthesis Protocol

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Fmoc-OSu and other Fmoc-amino acids were obtained from GL Biochem (Shanghai, China). 2-Cl-trityl chloride resin (1.0–1.2 mmol/g) was obtained from Nankai University Resin Co. Ltd. Rhodamine B isothiocyanate (RBITC) was received from Aladdin. Paraformaldehyde was obtained from Beijing Solarbio Science & Technology Co., Ltd. Dulbecco’s modified Eagle’s medium (DMEM), fetal bovine serum (FBS) and penicillin/streptomycin were purchased from Gibco Corporation. All the other chemical reagents and solvents were purchased from Alfa (China) and used as received from commercial sources.
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