ITZ of pharmaceutical grade was purchased from Sanlian Pharmaceutical (Harbin, China), its active metabolite hydroxyitraconazole (OH-ITZ) (purity higher than 99%) was purchased from J&K Scientific Ltd. (Shanghai, China) and used as a reference substance. Commercial Sporanox® capsules were obtained from Xian Janssen Pharmaceutical Ltd. (Xian, China). d -α-tocopheryl polyethylene glycol 1000 succinate (TPGS), Poloxamer 188, and sodium dodecyl sulfate (SDS) were purchased from BASF (Ludwigshafen, Germany), Macklin Biochemical Ltd. (Shanghai, China), and FuchenChemical Reagents Factory (Tianjin, China), respectively. Hydroxypropylmethylcellulose acetate succinate (HPMC AS) (grade LF) was kindly provided by Shin Etsu (Shin-Etsu Chemical Co., Ltd., Tokyo, Japan). The beagle dogs used for in vivo bioavailability study were purchased from the ChaiMen Biological Technology Ltd. (Nanjing, China). HCl was obtained from Jinkun chemical co., Ltd (Bengbu, China), the Na3PO4, NaH2PO4 and Na2HPO4 were purchased from Damao Chemical Reagent Factory (Tianjin, China). All reagents were of grade analytical and used without further purification.
Na3po4
Manufactured by Tianjin Damao
Sourced in China
Na3PO4 is a chemical compound consisting of sodium, phosphorus, and oxygen. It is a white, crystalline solid that is soluble in water. Na3PO4 is commonly used as a laboratory reagent and in various industrial applications.
Automatically generated - may contain errors
2 protocols using na3po4
1
Bioavailability Enhancement of Itraconazole
2
Fluorescent Sensor for Biothiol Detection
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All reagents and solvents were purchased from Shanghai Aladdin Chemical Reagent Co. Ltd and used without further puri cation. All metal ions exist in the form of chlorides (NaCl, KCl, CaCl 2 , MgCl 2 , AlCl 3 , ZnCl 2 , MnCl 2 , HgCl 2 , FeCl 2 , CuCl 2 , FeCl 3 ), all anions exist in the form of sodium salts (NaF, NaCl, NaBr, NaI, NaHCO 3 , CH 3 COONa, NaNO 2 , NaNO 3 , Na 2 SO 3 , Na 2 SO 4 , NaH 2 PO 4 , Na 3 PO 4 , NaClO, C 6 H 5 Na 3 O 7 , Na 2 S) and biothiols (Cys, Hcy and GSH) were purchased from Tianjin Damao Chemical Reagent Company. Na 2 S is used as a source of H 2 S. The other reagents used in the experiment were analytically pure, and the distilled water used was the secondary distilled water. The solvents used were all treated according to the manual of organic solvent puri cation. Instruments used in the experiment mainly include Mettler imported electronic balance, Swiss Mettler Toledo Instruments Co. Ltd. 1 H NMR spectra was measured using an Unity Plus-400-MHz spectrometer. HRMS was determined with a Mariner apparatus. UV-vis titration experiment was tested on a Shimadzu UV2600 Spectrophotometer. Fluorescence spectra was performed using an Eclipse Fluorescence Spectrophotometer. The uorescence lifetime was measured by transient/steady-state uorescence spectrometer FLS100.
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