DU145, CCRF-CEM, MOLT4, and K562 were obtained from the Division of Cancer Treatment (DCTD), Developmental Therapeutics Program (DTP, NCI), and EW8 and A673 are kind gifts from Dr. Lee Helman (NCI/NIH). All cells were grown in RPMI medium with 10% FBS (Gibco-BRL) at 37°C in 5% CO2. Information about the SCLC lines is shown in Table S2. The ATR inhibitor VE-821, olaparib, and veliparib were obtained from the DCTD. Talazoparib was provided by BioMarin Pharmaceutical Inc. Temozolomide (T2577) and methyl methanesulfonate MMS (129925) were purchased from Sigma-Aldrich.
Temozolomide t2577
Manufactured by Merck Group
Temozolomide (T2577) is a chemical compound used in laboratory research. It is a synthetic alkylating agent with the molecular formula C6H12N2O2. Temozolomide is commonly used as a reference standard or for the preparation of test samples in various in vitro and in vivo studies.
Automatically generated - may contain errors
2 protocols using temozolomide t2577
1
Cell Lines and Reagents for Cancer Research
2
Transformed Mesenchymal Cell Line and T-Cell Leukemia
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Following the long-term culturing of bone marrow-derived rat mesenchymal cells, a transformed mesenchymal cell (rTMSC) line with maintained stemness properties was developed. The cell line formed soft-tissue fibrosarcomas in immunocompromised mice and syngeneic immunocompetent rats.12 (link)
Roser's leukemia is a transplantable radiation-induced acute T-cell leukemia induced in PVG rats.37 (link)
LTX-315 (K-K-W-W-K-K-W-Dip-K-NH2) was purchased from Bachem AG and prepared on request. Dip is the aromatic non-coded amino acid β-diphenylalanine. Dacarbazine (D2390), temozolomide (T2577) and cis-diammineplatinum(II) dichloride (P4394) were all purchased from Sigma-Aldrich.
Roser's leukemia is a transplantable radiation-induced acute T-cell leukemia induced in PVG rats.37 (link)
LTX-315 (K-K-W-W-K-K-W-Dip-K-NH2) was purchased from Bachem AG and prepared on request. Dip is the aromatic non-coded amino acid β-diphenylalanine. Dacarbazine (D2390), temozolomide (T2577) and cis-diammineplatinum(II) dichloride (P4394) were all purchased from Sigma-Aldrich.
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