All scanning was conducted on a General Electric 3T MR750 System (General Electric Healthcare, Milwaukee, WI) with Twin Speed gradients and a GE 8-channel head coil at the Center of Functional MRI at UCSD. See the supplement for more details.
Twin speed gradients
Manufactured by GE Healthcare
The Twin Speed Gradients is a laboratory equipment designed to generate two distinct gradient profiles simultaneously. It provides precise control over the gradients, allowing researchers to conduct multiple experiments in parallel. The device is capable of creating linear and step gradients at independent flow rates, facilitating efficient sample separation and analysis.
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2 protocols using twin speed gradients
1
Structural Brain Imaging with 3T MRI
2
3D T1-Weighted MRI and BOLD Imaging Protocol
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Images were acquired on a General Electric Signa 3.0-T scanner equipped with 40 mT/m TwinSpeed gradients and Quiet Technology. A 3D T1-weighted Fast SPGR Sequence with188 sagittal slices (1 mm thickness) with a voxel size of 1.02 × 1.02 mm was used for the acquisition of anatomical data. To acquire BOLD (Blood Oxygenation Level Dependent) data, a total of 320 EPI-volumes were collected, 80 volumes per run, with the following parameter: TR = 3.0 s, TE = 30 ms, 1.72 × 1.72 mm in-plane voxels, 128 × 128 matrix, slice thickness 3.5 mm, 0.5 mm gap, and 35 axial slices. Each ON-block allowed the acquisition of eight full scans, and the same for each OFF-block. Each run was preceded by eight dummy scans in order to assure signal saturation of the cerebrospinal fluid facilitating steady state signal intensity.
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