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Balb c jax 651

Manufactured by Jackson ImmunoResearch

BALB/c (JAX 651) is a widely used inbred mouse strain. It is commonly used as a model for immunological and cancer research.

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2 protocols using balb c jax 651

1

Generation and Characterization of Transgenic Mice

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C57BL/6 (B6) mice were purchased from Taconic Farms (Hudson, NY). B6.SJL (CD45.1/1), B6.SJL/C57BL/6 (CD45.1/2) mice were obtained through a supply contract between the National Institute of Allergy and Infectious Diseases (NIAID) and Taconic Farms. Epx-Cre mice (Doyle et al., 2013 (link)) were initially obtained from Elizabeth Jacobsen (Mayo Clinic, Phoenix, AZ) and subsequently crossed to ROSA26-LSL-tdTomato mice to generate eosinophil-specific fluorescent EPX-reporter animals and generously gifted by David Sacks (NIAID) (Lee et al., 2020b (link)). Gpr183−/− mice (Baptista et al., 2019 (link); Liu et al., 2011 (link)) were gifted by Michael Fessler (NIEHS) and Vanja Lazarevic (NCI). Ccr3−/− (JAX 5440, C.129S4-Ccr3tm1Cge/J) on the BALB/c background, BALB/c (JAX 651), BALB/c CD45.1 (JAX 6584, CByJ.SJL(B6)-Ptprca/J) and Ch25h−/− (JAX 16263, B6.129S-Ch25htm1Rus/J) mice were purchased from Jackson Laboratories (Bar Harbor, ME). Both male and female mice, 8–24 wk. old at onset of experiments were used and experimental groups in individual experiments were age and sex matched. All animals were bred and maintained in an AAALAC-accredited ABSL2 or ABSL3 facility at the NIH and experiments performed in compliance with an animal study proposal approved by the NIAID Animal Care and Use Committee (protocol LCIM17E).
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2

Generation and Characterization of Transgenic Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols
C57BL/6 (B6) mice were purchased from Taconic Farms (Hudson, NY). B6.SJL (CD45.1/1), B6.SJL/C57BL/6 (CD45.1/2) mice were obtained through a supply contract between the National Institute of Allergy and Infectious Diseases (NIAID) and Taconic Farms. Epx-Cre mice (Doyle et al., 2013 (link)) were initially obtained from Elizabeth Jacobsen (Mayo Clinic, Phoenix, AZ) and subsequently crossed to ROSA26-LSL-tdTomato mice to generate eosinophil-specific fluorescent EPX-reporter animals and generously gifted by David Sacks (NIAID) (Lee et al., 2020b (link)). Gpr183−/− mice (Baptista et al., 2019 (link); Liu et al., 2011 (link)) were gifted by Michael Fessler (NIEHS) and Vanja Lazarevic (NCI). Ccr3−/− (JAX 5440, C.129S4-Ccr3tm1Cge/J) on the BALB/c background, BALB/c (JAX 651), BALB/c CD45.1 (JAX 6584, CByJ.SJL(B6)-Ptprca/J) and Ch25h−/− (JAX 16263, B6.129S-Ch25htm1Rus/J) mice were purchased from Jackson Laboratories (Bar Harbor, ME). Both male and female mice, 8–24 wk. old at onset of experiments were used and experimental groups in individual experiments were age and sex matched. All animals were bred and maintained in an AAALAC-accredited ABSL2 or ABSL3 facility at the NIH and experiments performed in compliance with an animal study proposal approved by the NIAID Animal Care and Use Committee (protocol LCIM17E).
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