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Bicalutamide

Manufactured by LKT Laboratories

Bicalutamide is a pharmaceutical compound used as a lab equipment product. It is an antiandrogen, which means it blocks the action of male hormones, such as testosterone. This compound is commonly used in research and laboratory settings to study its effects on biological systems.

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2 protocols using bicalutamide

1

Evaluating Docetaxel and Bicalutamide Sensitivity

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Docetaxel (CAS#114977-28-5) was purchased from TSZ CHEM (Framingham, MA). Bicalutamide (Cat: #B3209) were purchased from LKT Laboratories, Int. Elacridar (Cat: #143664-11-3) and Rhodamine 123 (Cat: #62667-70-9) were purchased from Sigma-Aldrich. Anti-ser15 phosphorylated p53 antibody was obtained from Cell Signaling Technology, Int. Cleaved PARP, wt-p53 and tubulin antibodies were obtained from Santa Cruz Biotechnologies (Santa Cruz, CA).
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2

Tasquinimod Metabolite Preparation

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Ketoconazole and bicalutamide (i.e., casodex) were obtained from LKT Laboratories Inc. (St Paul, MN). Unlabeled tasquinimod and 14C-tasquinimod labeled in the 3 position of the quinoline nucleus at a specific activity of 33.9 mCi/mmol (> 90% purity) were provided by Active Biotech Inc. AB. Tasquinimod metabolites were prepared at Active Biotech AB (Lund, Sweden) as previously described [7 (link), 12 (link)].
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