MRI data were acquired at four sites on scanners from three vendors: Children's Hospital of Los Angeles (Philips Achieva); University of California – San Diego (General Electric MR750); University of Minnesota and Emory University (both Siemens Tim Trio). The acquisition sequence was modeled after protocols developed for multi-site imaging by the Pediatric Imaging Neurocognition and Genetics (PING) group (Table 2 ) (http://ping.chd.ucsd.edu ). The protocol included several scans, however, only the high-resolution T1-weighted scan was used in this analysis. Acquisition parameters are shown in Table 2 . Participants were not sedated for the MRI scan nor were their usual medications modified.
Mr750
Manufactured by Siemens
The MR750 is a laboratory equipment product manufactured by Siemens. It is a magnetic resonance imaging (MRI) system designed for research and clinical applications. The MR750 provides high-quality imaging capabilities, allowing for the visualization and analysis of various biological structures and processes. The specific details and intended use of this product are not included in this factual description.
Automatically generated - may contain errors
Lab products found in correlation
Prisma, by Siemens (4 mentions)
Tim trio, by Siemens (3 mentions)
Achieva, by Siemens (2 mentions)
Mr750w, by GE Healthcare (2 mentions)
Tim trio, by GE Healthcare (1 mentions)
Mr750w, by Siemens (1 mentions)
Mr750, by GE Healthcare (1 mentions)
Ingenia scanner, by Philips (1 mentions)
Prisma, by Philips (1 mentions)
9 protocols using mr750
1
Multi-Site MRI Protocol for Pediatric Imaging
2
Multisite fMRI Imaging Acquisition Protocol
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All fMRI scans were conducted on 3 T scanners at Yale University, Columbia University, or University of California at Davis on the following scanners respectively: 3 T Siemens TIM TRIO, 3 T GE MR750, and 3 T Siemens TIM TRIO. All sites used a 32-channel head coil. The same scanning parameters were used across all sites (detailed scanner specifications can be found in Javitt et al., 2018 (link)). Briefly, before initial resting state scans, high-resolution T1*weighted anatomical images were acquired for image registration (TR = 1900 ms, TE = 2.98 ms, TI = 1100 ms, matrix = 256 × 256, FOV = 256 mm, voxel size = 1.0 × 1.0 × 1.0mm). Then for both pre-drug baseline and post-drug functional imaging, 32 axial-oblique slices were obtained in an interleaved pattern (TR = 200 ms, TE = 30.0ms, FOV = 220 mm, matrix = 64*64, slice thickness = 4 .0mm, one voxel = 3.4 × 3.4 × 4.0mm).
3
Whole-Brain Diffusion-Weighted Imaging Protocol
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The whole-brain diffusion-weighted image acquisition protocol and approach to quality assurance38 (link) was previously described.36 Whole-brain diffusion-weighted images were acquired using 30 different gradient directions at b = 900 s/mm2 and 5 at b = 0 s/mm2, with 2.2 mm isotropic resolution. Sites with General Electric scanners used repetition time (TR)/echo time (TE) = 6 s/70 ms (MR750; Montreal and Vancouver) or TR/TE = 12 s/90 ms (MR750w; Calgary); sites with Siemens scanners used TR/TE = 6.3/55 ms (Prisma; Edmonton and Montreal) or TR/TE = 7.8 s/90 ms (Skyra; Ottawa).
4
Multimodal Neuroimaging in Post-Acute TBI
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Participants completed T1-weighted and diffusion imaging at the post-acute assessment between 2 and 23 days (mean 11.56 ± 5.43) post injury. 75.5% of participants were imaged within 14 days post-injury, with 46% imaged between 7 and 14 days after injury. Images were acquired on a 3 T scanner at each site (General Electric MR750w in Calgary; General Electric MR750 and Siemens Prisma in Montreal, General Electric MR750 in Vancouver; Siemens Prisma in Edmonton; Siemens Skyra in Ottawa).
5
Autism Neuroimaging Dataset (ABIDE-II)
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The ABIDE-II project consists of 521 autistic patients from 19 different sites [31 (link)] (http://fcon_1000.projects.nitrc.org/indi/abide/abide_II.html). We used stratified sampling to select 30 patients from the full dataset. The sampling data were acquired using a Philips Achieva 1.5 T scanner and various other 3 T scanners, including the GE MR750, Siemens TriTim, Allegra, and Skyra scanners, and a Philips Ingenia scanner. The spatial resolutions of sampled data varied from 0.7 to 1.3 mm. Prior to data collection, all sites were required to confirm that their local Institutional Review Board (IRB) or ethics committee have approved study procedures. Scanning protocols and demographics of this dataset were described in a previous report published by [31 (link)].
6
Multisite MRI Imaging at 3T
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7
Multimodal Brain Imaging Protocol
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Eleven participants were scanned twice using a 3T General Electric MR750, and nine participants were scanned twice using a 3T Siemens Prisma scanner due to scanner upgrade, equipped with a 32‐channel receive‐only head coil. Each participant was scanned twice with the same scanner. For each participant a high‐resolution T1‐weighted sequence was acquired using the following parameter: T1 = 450 ms (GE) or 900 ms (Siemens), Flip angle = 12° (GE) or 8° (Siemens), 256 × 256 matrix, slice thickness = 1 mm. T2*‐weighted echo‐planar images (EPIs) depicting the blood‐oxygen‐level‐dependent (BOLD) were acquired for each participant with TR = 1.3 s (GE) or 1.5 s (Siemens), TE = 28 ms, FA = 60° (GE) or 75° (Siemens), FOV = 19.2 cm, number of slices = 27, slice thickness = 4 mm. A head cushion limited head motion.
DTI data were obtained in the axial plane using a single‐shot diffusion‐weighted echo planar imaging sequence with the following parameters: TR/TE = 8500/77ms, FOV = 240mm, matrix size = 122×122, slice thickness = 2.5 mm, number of slices = 60, number of diffusion gradient directions = 64, b‐value = 1000 s/mm2, number of images at b‐value of 0 s/mm2 = 5, acceleration factor = 2. The scanner factor was controlled as a covariate of no‐interest in all three modalities analysis.
DTI data were obtained in the axial plane using a single‐shot diffusion‐weighted echo planar imaging sequence with the following parameters: TR/TE = 8500/77ms, FOV = 240mm, matrix size = 122×122, slice thickness = 2.5 mm, number of slices = 60, number of diffusion gradient directions = 64, b‐value = 1000 s/mm2, number of images at b‐value of 0 s/mm2 = 5, acceleration factor = 2. The scanner factor was controlled as a covariate of no‐interest in all three modalities analysis.
8
High-Resolution 3D MRI Scanning for the ABCD Study
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Scan sessions are conducted at each ABCD site using either a GE MR750, Siemens PRISMA or Philips scanner, all equipped with a 32-channel head coil. See Table 2 for scan parameters. A 3D T1-weighted magnetization-prepared rapid acquisition gradient-echo scan using prospective motion correction (PROMO) is used to obtain a high-resolution anatomical image for cortical and subcortical segmentation. PROMO technology allows for ability to correct for motion in real-time (45 (link)) and has been demonstrated as particularly beneficial for scanning children who have more difficulty staying still (46 (link), 47 (link)). For further review of imaging acquisition and processing methods used in the ABCD study see Hagler et al. (48 (link)).
9
Multi-Site Pediatric MRI Imaging Protocol
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