Log In Sign up
The largest database of trusted experimental protocols

Nsg β2m mice

Manufactured by Jackson ImmunoResearch
Visit Supplier
Sourced in Montenegro

NSG-β2m–/– mice are a type of laboratory mouse model that have been genetically modified to lack the beta-2 microglobulin (β2m) gene. These mice have a severely compromised immune system, making them a useful tool for research involving the study of human cells and tissues in a living organism.

Automatically generated - may contain errors

Lab products found in correlation

Spelling variants of this product

NSG mice (401 citations) β2m−/− mice (6 citations)

2 protocols using nsg β2m mice

1

Breeding and Maintaining C57BL/6 and NSG-β2m−/− Mice

Check if the same lab product or an alternative is used in the 5 most similar protocols
C57BL/6 mice were bred and maintained in microisolator cages under SPF conditions in accordance with the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) guidelines at the NIH. NSG-β2m–/– mice were obtained from the Jackson Laboratory, and they were bred and maintained in accordance with AAALAC guidelines. All animal studies were performed following approval from the NIH IACUC (protocol no. LTIB-057).
Pellom S.T., Smalley Rumfield C., Morillon YM I.I., Roller N., Poppe L.K., Brough D.E., Sabzevari H., Schlom J, & Jochems C. (2021). Characterization of recombinant gorilla adenovirus HPV therapeutic vaccine PRGN-2009. JCI Insight, 6(7), e141912.
+ Open protocol
+ Expand
2

NSG-β2m Knockout Mouse Husbandry

Check if the same lab product or an alternative is used in the 5 most similar protocols
NSG-β2m−/− mice were obtained from the Jackson Laboratory (Bar Harbor, ME) and bred and maintained in microisolator cages under SPF conditions in accordance with AAALAC guidelines. All animal studies were performed following approval from the NIH Intramural Animal Care and Use Committee.
Morillon YM I.I., Smalley Rumfield C., Pellom S.T., Sabzevari A., Roller N.T., Horn L.A., Jochems C., Palena C., Greiner J.W, & Schlom J. (2020). The Use of a Humanized NSG-β2m−/− Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa. Frontiers in Oncology, 10, 549.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!