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Xrcc1

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XRCC1 is a DNA repair protein that plays a crucial role in the base excision repair (BER) pathway. It functions as a scaffold, coordinating the activities of various enzymes involved in the repair of single-strand DNA breaks and base damage. XRCC1 facilitates the recruitment and assembly of the BER complex, enabling the efficient and accurate repair of DNA lesions.

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Lab products found in correlation

5mc clone 33d3, by Diagenode (2 mentions) Img 268a, by Abnova (2 mentions) Dnmt3l, by Abnova (2 mentions) Pab2230, by Abnova (2 mentions) H3k36me3, by Abcam (2 mentions)

2 protocols using xrcc1

1

Epigenetic Modifications Profiling

Check if the same lab product or an alternative is used in the 5 most similar protocols
XRCC1 (Serotec) 1:200, 5mC (clone 33D3, Diagenode) 1:5000 (0.02 ug/ml), 5hmC (Active Motif) 1:500 (2 ug/ml), H3K9me2 (07-441, Upstate) 1:400, H3K27me3 (gift from Dr. T. Jenuwein) 1:500, H3K4me2 (07-030, Upstate) 1:500, H3K36me3 (gift from Dr. H. Kimura,) 1:50, TET3 (C-term, Abcam) 1:200, Dnmt3a (Imgenex, IMG-268A) 1:200, Dnmt3L (Abnova, PAB2230) 1:100.
Amouroux R., Nashun B., Shirane K., Nakagawa S., Hill P.W., D’Souza Z., Nakayama M., Matsuda M., Turp A., Ndjetehe E., Encheva V., Kudo N.R., Koseki H., Sasaki H, & Hajkova P. (2016). De novo DNA methylation drives 5hmC accumulation in mouse zygotes. Nature cell biology, 18(2), 225-233.
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2

Epigenetic Modifications Profiling

Check if the same lab product or an alternative is used in the 5 most similar protocols
XRCC1 (Serotec) 1:200, 5mC (clone 33D3, Diagenode) 1:5000 (0.02 ug/ml), 5hmC (Active Motif) 1:500 (2 ug/ml), H3K9me2 (07-441, Upstate) 1:400, H3K27me3 (gift from Dr. T. Jenuwein) 1:500, H3K4me2 (07-030, Upstate) 1:500, H3K36me3 (gift from Dr. H. Kimura,) 1:50, TET3 (C-term, Abcam) 1:200, Dnmt3a (Imgenex, IMG-268A) 1:200, Dnmt3L (Abnova, PAB2230) 1:100.
Amouroux R., Nashun B., Shirane K., Nakagawa S., Hill P.W., D’Souza Z., Nakayama M., Matsuda M., Turp A., Ndjetehe E., Encheva V., Kudo N.R., Koseki H., Sasaki H, & Hajkova P. (2016). De novo DNA methylation drives 5hmC accumulation in mouse zygotes. Nature cell biology, 18(2), 225-233.
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