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Zomepirac sodium salt

Manufactured by Merck Group
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Sourced in Germany

Zomepirac sodium salt is a chemical compound used as a laboratory reagent. It functions as a sodium salt, providing a source of the zomepirac anion for various research and analytical applications.

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Lab products found in correlation

Formic acid, by Merck Group (5 mentions) Lc grade ethanol, by Merck Group (4 mentions) Api tof reference mass solution kit, by Agilent Technologies (4 mentions) Esi tof biopolymer analysis reference masses, by Agilent Technologies (4 mentions) Milli q integral 3 system, by Merck Group (3 mentions) Ls ms grade acetonitrile, by Merck Group (3 mentions) Methanol, by Merck Group (3 mentions) Esi l low concentration tuning mix g1969 85000, by Agilent Technologies (2 mentions) Milli q integral three system, by Merck Group (2 mentions) Lc ms grade methanol, by Merck Group (2 mentions) Acetonitrile, by Merck Group (2 mentions) Esi l low concentration tuning mix, by Agilent Technologies (2 mentions) Pure p a ammonium solution, by Avantor (2 mentions) Hypoxanthine, by Merck Group (1 mentions) L lactic acid, by Merck Group (1 mentions) L pyroglutamic acid, by Merck Group (1 mentions) L histidine monohydrochloride monohydrate, by Merck Group (1 mentions) Oleic acid, by Merck Group (1 mentions) Arachidonic acid, by Merck Group (1 mentions) Docosahexaenoic acid, by Merck Group (1 mentions)

6 protocols using zomepirac sodium salt

1

Characterization of Biological Compounds

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Purified water was obtained by using a Milli-Q Integral 3 system (Millipore SAS, Molsheim, France). Zomepirac sodium salt (used as internal standard, IS), L-pyroglutamic acid, hypoxanthine, L-histidine monohydrochloride monohydrate, oleic acid, L(+) lactic acid, LS-MS grade acetonitrile, methanol, formic acid, and LC grade ethanol were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). The API-TOF reference mass solution kit (G1969-850001) and tuning solutions, ESI-L low-concentration tuning mix (G1969-85000), and ESI-TOF Biopolymer Analysis reference masses (G1969-850003) were purchased from Agilent Technologies (Santa Clara, CA, USA).
Szeremeta M., Samczuk P., Pietrowska K., Kowalczyk T., Przeslaw K., Sieminska J., Kretowski A., Niemcunowicz-Janica A, & Ciborowski M. (2022). In Vitro Animal Model for Estimating the Time since Death with Attention to Early Postmortem Stage. Metabolites, 13(1), 26.
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2

Preparation of Aqueous Solutions

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Ultrapure water was used to prepare all the aqueous solutions and was obtained “in-house” from a Milli-Q Integral three system (Millipore, SAS, Molsheim, France). Zomepirac sodium salt, formic acid, LC-MS-grade methanol and acetonitrile, and LC-grade ethanol were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany).
Sieminska J., Miniewska K., Mroz R., Sierko E., Naumnik W., Kisluk J., Michalska-Falkowska A., Reszec J., Kozlowski M., Nowicki L., Moniuszko M., Kretowski A., Niklinski J., Ciborowski M, & Godzien J. (2024). First insight about the ability of specific glycerophospholipids to discriminate non-small cell lung cancer subtypes. Frontiers in Molecular Biosciences, 11, 1379631.
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3

Quantitative Lipidomic Analysis Protocol

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Blank samples included mixtures of methanol/ethanol (1:1) that were prepared in the same way as biological samples. Zomepirac sodium salt (used as the internal standard (IS), arachidonic acid, docosahexaenoic acid, lysophosphatidylethanolamine (LPE) 18:0, phosphatidylethanolamine (PE) 16:0/22:6, LS-MS-grade acetonitrile, methanol, LC-grade formic acid, and ethanol were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). The API-TOF reference mass solution kit (G1969-850001) and tuning solutions, ESI-L low-concentration tuning mix (G1969-85000), and ESI-TOF Biopolymer Analysis reference masses (G1969-850003) were purchased from Agilent Technologies (Santa Clara, CA, United States). Purified water was obtained using the Milli-Q Integral three system (Millipore SAS, Molsheim, France) in order to prepare solution A.
Małachowska B., Pietrowska K., Młynarski W., Szadkowska A., Krętowski A., Ciborowski M, & Fendler W. (2022). Multi-Timepoint Metabolic Fingerprinting of a Post-Episode Period of Hypoglycemia and Ketoacidosis Among Children With Type 1 Diabetes. Frontiers in Molecular Biosciences, 9, 869116.
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4

Ultrapure Water Preparation for Analytical Experiments

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Ultrapure water was used to prepare all aqueous solutions and was obtained using a Milli-Q Integral 3 system (MilliporeSigma, Burlington, MA, United States). Zomepirac sodium salt, formic acid, LC-MS-grade methanol, acetonitrile, and LC-grade ethanol were purchased from Sigma-Aldrich (St. Louis, MO, United States).
Godzien J., Lopez-Lopez A., Sieminska J., Jablonowski K., Pietrowska K., Kisluk J., Mojsak M., Dzieciol-Anikiej Z., Barbas C., Reszec J., Kozlowski M., Moniuszko M., Kretowski A., Niklinski J, & Ciborowski M. (2024). Exploration of oxidized phosphocholine profile in non-small-cell lung cancer. Frontiers in Molecular Biosciences, 10, 1279645.
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5

Mass Spectrometry Protocol for Metabolite Analysis

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Purified water was obtained using the Milli-Q Integral 3 system (Millipore SAS, Molsheim, France). Zomepirac sodium salt (used as an internal standard, IS), L-serine, L-arginine hydrochloride monohydrate, ascorbic acid, L-homoarginine hydrochloride, LC-MS grade methanol acetonitrile, formic acid and LC grade ethanol were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). Pure p. a. ammonium solution (25%) was purchased from Avantor Performance Materials (Gliwice, Poland). The API-TOF reference mass solution kit (G1969–850001) and tuning solutions, ESI-L low concentration tuning mix (G1969–85000) and ESI-TOF Biopolymer Analysis reference masses (G1969–850003) were purchased from Agilent Technologies (Santa Clara, California, United States).
Dmuchowska D.A., Pietrowska K., Krasnicki P., Kowalczyk T., Misiura M., Grochowski E.T., Mariak Z., Kretowski A, & Ciborowski M. (2021). Metabolomics Reveals Differences in Aqueous Humor Composition in Patients With and Without Pseudoexfoliation Syndrome. Frontiers in Molecular Biosciences, 8, 682600.
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6

Mass Spectrometry Protocol Optimization

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Purified water was obtained using the Milli-Q Integral 3 system (Millipore SAS, Molsheim, France). Zomepirac sodium salt (used as internal standard, IS), LS-MS-grade acetonitrile (ACN), methanol (MeOH), and formic acid (FA) were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). Pure p.a. ammonium solution (25%) was purchased from Avantor Performance Materials (Gliwice, Poland). The API-TOF reference mass solution kit (G1969-850001) and tuning solutions, ESI-L low concentration tuning mix (G1969-85000), and ESI-TOF Biopolymer Analysis reference masses (G1969-850003) were purchased from Agilent Technologies (Santa Clara, CA, USA). Standards to confirm the identity of metabolites were purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany) (taurine, pipecolic acid, leucine, histidine, phenylalanine, 3-methylhistidine, citric acid, tryptophan, adenosine, and stearoylcarnitine) and Avanti Polar Lipids Inc. (AL, USA) (LPI 18:0 and LPG 18:1).
Krupska O., Kowalczyk T., Beręsewicz-Haller M., Samczuk P., Pietrowska K., Zabłocki K., Kretowski A., Ciborowski M, & Zabłocka B. (2020). Hippocampal Sector–Specific Metabolic Profiles Reflect Endogenous Strategy for Ischemia-Reperfusion Insult Resistance. Molecular Neurobiology, 58(4), 1621-1633.
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