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Ti cron

Manufactured by Medtronic
Sourced in United States

The Ti-cron is a laboratory equipment product designed for specific tasks. It functions as a precision tool for researchers and scientists. The core purpose of the Ti-cron is to perform accurate measurements and analyses within a controlled laboratory environment.

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5 protocols using ti cron

1

Laparoscopic Hiatal Hernia Repair with Nissen Fundoplication

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All procedures were performed laparoscopically. After repositioning the stomach and dissecting the hernia sac, the hiatus was closed using non-absorbable woven sutures (Ti-cron™, Covidien, New Haven, CT, USA). In several cases, the cruroplasty was reinforced using a prosthetic mesh (Parietex™, Covidien) at the discretion of the operating surgeon. This was then followed by a 360-degree floppy Nissen fundoplication. We did not perform gastropexy or a gastrostomy. The most distal suture fixates the wrap to the wall of the esophagus to prevent telescoping.
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2

Laparoscopic Nissen Fundoplication for GERD

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All procedures were performed laparoscopically. In all patients, the hiatus was dissected completely and a posterior cruroplasty was performed using non-absorbable braided sutures (Ti-cron™, Covidien, New Haven, CT, USA). The patency must be at least 10 mm besides the oesophagus. If a large hiatal hernia was present, the cruroplasty was reinforced using a non-absorbable prosthetic mesh (Parietex™, Covidien, New Haven, CT, USA) at the discretion of an operating surgeon. After dissection of the short gastric vessels, a 360° floppy Nissen fundoplication was created. We did not use a boogie to calibrate the fundoplication. The most distal suture fixates the wrap to the wall of the oesophagus to prevent telescoping. We did not perform any gastropexy. The patient did receive neither post-operative drain nor epidural analgesia.
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3

Suture Materials Characterization Protocols

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Seven suture materials (VICRYL®, MONOCRYL®, Ethilon®, Perma-Hand®, Ethibond EXCEL®, (Ethicon Inc.®, New Jersey, USA), Ti-Cron® (Covidien®, Dublin, Republic of Ireland) and FiberWire® (Athrex®, Florida, USA)) were sourced from our local hospital. Suture materials were obtained pre-sterilised by gamma-irradiation and packaged for clinical use. Respective sutures were cut into homogenous 5mm sections, placed into 24-well tissue culture plates, and pre-soaked in Roswell Park Memorial Institute (RPMI) cell media (Invitrogen™, ThermoFisher Scientific, Australia) for 24 hours. Sterile conditions were maintained in class II laminar flow hoods.
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4

Ex-cuff Suture Occlusion Technique

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A polyester suture (Ti-Cron™; Medtronic, Minneapolis, MN, USA) was inserted through the center or upper one-third of the Ex-cuff to secure the thread and drawn around the Ex-cuff to form a diameter-reducing tie. Complete ligation was achieved with a clearance of approximately 10 mm. A 2F oversized delivery sheath is required to allow the suture stent-graft insertion; thus, a 20-F sheath was required when a 36-mm Ex-cuff was used. A 16-mm AVP I was deployed in the waist of the Ex-cuff to complete occlusion.
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5

Supraspinatus Tendon Repair Techniques

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After 6 weeks, the torn supraspinatus tendon was repaired as follows: under the same anesthesia and approach, the Penrose drains (Yushin Corp.) were removed and the greater tuberosity was prepared with a scalpel blade. Two interosseous bone tunnels were created at the anterior and posterior aspects of the footprint and 5 mm distal to the articular surface. Size 2-0 Ti-Cron (Medtronic, Minneapolis, MN, USA) nonabsorbable sutures were passed through the tunnels for reattaching the supraspinatus tendon to the footprint and then tied over the lateral humeral cortex (Fig. 3). The control group did not receive any surgery. In the repair + PRP (RP) group, we injected 0.5 mL of the prepared PRP without dilution into the supraspinatus muscle adjacent to the repair site. In the repair + BMAC (RB) group, we injected 0.5 mL of BMAC. The repair + PRP + BMAC (RPB) group was injected with 0.25 mL PRP + 0.25 mL of BMAC. In the repair + saline (RS) group, we injected 0.5 mL of saline. Every injection was administered in the repair site, footprint of the supraspinatus tendon, after the repair and the overall volume of injection were the same between the repair groups. The incision was closed in the same manner as described above, and the rabbits were allowed free cage activity without limb immobilization.
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