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P tau

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P-Tau is a lab equipment product that measures phosphorylated tau protein. It is used to quantify the levels of this protein in biological samples.

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Lab products found in correlation

Total tau, by Thermo Fisher Scientific (1 mentions) β catenin, by Abcam (1 mentions)

2 protocols using p tau

1

Quantification of Alzheimer's Biomarkers

Cited 1 time
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The Aβ42, p-Tau, and total tau levels in the soluble fraction of frozen brain tissues were quantified using an ELISA assay (Aβ42; Thermo Fisher Scientific, p-Tau; MyBioSource, San Diego, CA, USA, and total tau; Invitrogen)23 (link). All assays were performed according to manufacturer instructions. Levels of these proteins were calculated from a standard curve developed with specific optical density versus serial dilutions of a known concentration. Each standard and experimental sample was run in duplicate, and the results were averaged23 (link).
Kang S., Kim J, & Chang K.A. (2021). Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model. Scientific Reports, 11, 1334.
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2

Quantifying Alzheimer's Biomarkers in Brain

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The brain contents of amyloid-β (Aβ) (catalog no. MBS702915, MyBioSource, San Diego, United States), phosphorylated tau (p-tau) (catalog no. MBS725098, MyBioSource, San Diego, United States), GSK-3β (catalog no. MBS3808332, MyBioSource, San Diego, United States), JAK-2 (catalog no. MBS2019409, MyBioSource, San Diego, United States), STAT-3 (catalog no. MBS760293, MyBioSource, San Diego, United States), β-catenin (catalog no. K3383, Biovision Inc.), Rat Wnt3a ELISA kit (catalog no. orb555678, Biorbyt Ltd., United Kingdom), TNF-α (catalog no. RTA00, Quantikine, R&D systems Europe, Abingdon, United Kingdom), IL-6β (catalog no. BMS625TEN, ThermoFisher Scientific Inc.), IL-1β (catalog no. BMS630, ThermoFisher Scientific Inc.), and caspase-3 (catalog no. CASP3C, ThermoFisher Scientific Inc.) were measured in brain homogenate using ELISA kits according to the manufacturer’s instructions.
Abu-Elfotuh K., Selim H.M., Riad O.K., Hamdan A.M., Hassanin S.O., Sharif A.F., Moustafa N.M., Gowifel A.M., Mohamed M.Y., Atwa A.M., Zaghlool S.S, & El-Din M.N. (2023). The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways. Frontiers in Pharmacology, 14, 1208252.
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