2(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate (HBTU) and the N-hydroxybenzotriazole (HOBt) were purchased from Vivitide (Gardner, MA). All protected amino acids, rink amide MBHA resin, and N-methylmorpholine (NMM) were supplied by Gyros Protein Technologies (Tucson, AZ). Polyethylene glycol (PEG3) was obtained from Creative PEGWorks (Durham, NC). Trifluoroacetic acid (TFA), piperidine, thioanisole, anisole, 1,2-ethanedithiole, methyl-tert-butyl ether, N,N-diisopropylethylamine (DIPEA), dimethylformamide (DMF), acetonitrile (ACN), N-methyl-2-pyrrolidone (NMP), sodium carbonate, Sephadex G25, L-glutathione reduced (GSH), lipopolysaccharide (LPS), and cis-dichlorodiammine platinum (II) (cisplatin) were purchased from Sigma Aldrich (Saint-Louis, MO). Succinimidyl 3-(2-pyridyldithio)propionate (SPDP) was supplied by Invitrogen (Carlsbad, CA). p-SNC-deferoxamine (DFO) was from Macrocyclics Inc. (Plato, TX). N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)-maytansine (DM1) and aldoxorubicin HCl (aldox) were from MedKoo Biosciences (Morrisville, NC). Doxorubicin (DOX) and gemcitabine (GEM) were obtained from LC Laboratories (Woburn, MA). Mitomycin (MIT) was supplied by Selleckchem (Houston, TX). Cyanine5.5 NHS ester was purchased from Lumiprobe Corporation (Hallandale Beach, FL) and luciferin was from Caliper LifeScience (Hopkinton, MA).
N2 deacetyl n2 3 mercapto 1 oxopropyl maytansine dm1
Manufactured by MedKoo Biosciences
N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine (DM1) is a chemical compound that serves as a component in the development of antibody-drug conjugates (ADCs). It is a derivative of the natural product maytansine, which has cytotoxic properties. DM1 can be used in the manufacturing and research of ADCs, which are a class of targeted cancer therapies.
Automatically generated - may contain errors
Lab products found in correlation
Thioanisole, by Merck Group (2 mentions)
Anisole, by Merck Group (2 mentions)
Rink amide mbha resin, by Gyros Protein Technologies (2 mentions)
Polyethylene glycol peg3, by Creative PEGWorks (2 mentions)
Cisplatin cis dichlorodiammine platinum 2, by Merck Group (2 mentions)
Aldoxorubicin hcl aldox, by MedKoo Biosciences (2 mentions)
N n diisopropylethylamine, by Merck Group (2 mentions)
Sephadex g 25, by Merck Group (2 mentions)
1 2 ethanedithiole, by Merck Group (2 mentions)
Acetonitrile, by Merck Group (2 mentions)
Sodium carbonate, by Merck Group (2 mentions)
Dimethylformamide, by Merck Group (2 mentions)
Doxorubicin dox, by LC Laboratories (2 mentions)
Cyanine5.5 nhs ester, by Lumiprobe (2 mentions)
P snc deferoxamine dfo, by Macrocyclics (2 mentions)
Mitomycin, by Selleck Chemicals (1 mentions)
N methylmorpholine, by Gyros Protein Technologies (1 mentions)
Lipopolysaccharide, by Merck Group (1 mentions)
Trifluoroacetic acid, by Merck Group (1 mentions)
Methyl tert butyl ether (mtbe), by Merck Group (1 mentions)
2 protocols using n2 deacetyl n2 3 mercapto 1 oxopropyl maytansine dm1
1
Peptide Synthesis and Conjugation Protocol
2
Synthesis and Characterization of Peptide-Drug Conjugates
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
2(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate (HBTU) and the N-hydroxybenzotriazole (HOBt) were purchased from Vivitide. All protected amino acids, rink amide MBHA resin, and N-methylmorpholine (NMM) were supplied by Gyros Protein Technologies. Polyethylene glycol (PEG3) was obtained from Creative PEGWorks. Trifluoroacetic acid (TFA), piperidine, thioanisole, anisole, 1,2-ethanedithiole, methyl-tert-butyl ether, N,N-diisopropylethylamine (DIPEA), dimethylformamide (DMF), acetonitrile (ACN), N-methyl-2-pyrrolidone (NMP), sodium carbonate, Sephadex G25, L-glutathione reduced (GSH), lipopolysaccharide (LPS), and cis-dichlorodiammine platinum (II) (cisplatin) were purchased from Sigma-Aldrich. Succinimidyl 3-(2-pyridyldithio)propionate (SPDP) was supplied by Invitrogen. p-SNC-deferoxamine (DFO) was from Macrocyclics Inc. N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine (DM1) and aldoxorubicin HCl (aldox) were from MedKoo Biosciences. Doxorubicin (DOX) and GEM were obtained from LC Laboratories. MIT was supplied by Selleckchem. Cyanine5.5 NHS ester was purchased from Lumiprobe Corporation and luciferin was from Caliper LifeScience.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!