Slc11a2

Manufactured by Proteintech

Sourced in United States

SLC11A2 is a protein-coding gene that is responsible for the regulation of iron transport. It is expressed in various tissues and plays a crucial role in maintaining iron homeostasis within the body.

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Lab products found in correlation

Ab86707, by Abcam (1 mentions) Ab155282, by Abcam (1 mentions) Ab125066, by Abcam (1 mentions) Aicar, by Selleck Chemicals (1 mentions) Parp1 13371 1 ap, by Proteintech (1 mentions) Dhodh 14877 1 ap, by Proteintech (1 mentions) Mouse anti rat tfr1, by Thermo Fisher Scientific (1 mentions) Rabbit polyclonal anti mouse fpn1, by Novus Biologicals (1 mentions) Il 6 enzyme linked immunosorbent assay elisa kits, by R&D Systems (1 mentions) Aevertaid first strand cdna synthesis kit, by Thermo Fisher Scientific (1 mentions) Faststart universal sybr green master and lightcycler96, by Roche (1 mentions) Goat anti rabbit or anti mouse irdye 800 cw secondary antibody, by LI COR (1 mentions) Bca protein assay kit and protein ripa lysis buffer, by Beyotime (1 mentions) Trizol reagent, by Thermo Fisher Scientific (1 mentions)

2 protocols using slc11a2

Antibody and Reagent Inventory for Ferroptosis Research

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The antibodies to ACTB (66009-1-Ig), PARP1 (13371-1-AP), DHODH (14877-1-AP), G6PD (25413-1-AP), and solute carrier family 11 member 2 (SLC11A2, also known as DMT1; 20507-AP) were obtained from Proteintech Biotechnology. The antibodies to SLC25A22 (ab137614), GPX4 (ab125066), solute carrier family 7 member 11 (SLC7A11; ab216876), ACSL4 (ab155282), and NCOA4 (ab86707) were purchased from Abcam. The antibodies to SCD (A16429) were obtained from ABclonal.
The antibodies to AMPKα (5831) and phospho-AMPKα (Thr172; 2535) were obtained from Cell Signaling Technology. RSL3 (S8155), ferrostatin-1 (S7243), liproxstatin-1 (S7699), necrostatin-1 (S8037), Z-VAD-FMK (S7023), erastin (S7242), STS (S1421), OA (S4707), and AICAR (S1802) were purchased from Selleck Chemicals. A939572 (T4515) was purchased from TOPSCIENCE. Oxalacetic acid (328-42-7) was purchased from MACKLIN. GSH monoethyl ester (353905) and NAC amide (A0737) were purchased from MilliporeSigma. BODIPY 581/591 C11 (D3861) was obtained from Thermo Fisher Scientific.

Liu Y., Wang Y., Lin Z., Kang R., Tang D, & Liu J. (2023). SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids. Antioxidants & Redox Signaling, 39(1-3), 166-185.

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Iron Homeostasis Regulation in Mouse Macrophages

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Unless otherwise stated, all chemicals were obtained from the Sigma Chemical Company, St. Louis, MO, United States. Mouse anti-rat TfR1 (transferrin receptor 1) and fetal bovine serum (FBS) were purchased from Invitrogen, Carlsbad, CA, United States; rabbit polyclonal anti-mouse Fpn1 from Novus Biologicals, Littleton, CO, United States; rabbit polyclonal anti-Ft-L and anti-DMT1 (divalent metal transporter 1, SLC11A2) from Protein-tech, Chicago, IL, United States; and rabbit polyclonal anti-phospho-STAT3 (Tyr705) and mouse monoclonal anti-STAT3 both from Cell Signaling Technology, Inc., Danvers, MA, United States. Recombined mouse IL-6 protein was obtained from Gene Script, Piscataway, NJ, United States; IL-6 enzyme-linked immunosorbent assay (ELISA) kits from R&D Systems, Minneapolis, MN, United States; goat anti-rabbit or anti-mouse IRDye 800 CW secondary antibodies from LI-COR Bio Sciences, Lincoln, NE, United States; TRIzol reagent from Life Technologies, Carlsbad, CA, United States; AevertAid First Strand cDNA Synthesis Kit from Thermo Scientific, Waltham, MA, United States; FastStart Universal SYBR Green Master and LightCycler96 from Roche, Nutley, NJ, United States; and BCA protein Assay kit and protein RIPA lysis buffer from Beyotime Institute of Biotechnology, Haimen, JS, China.

Zhang F.L., Hou H.M., Yin Z.N., Chang L., Li F.M., Chen Y.J., Ke Y, & Qian Z.M. (2017). Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain. Frontiers in Molecular Neuroscience, 10, 367.

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