Compounds sofosbuvir (PSI-7977), telaprevir (VX-950), and simeprevir were purchased from MedChemExpress (Princeton, NJ). The monoantibody (mAb) to HCV Core (ab2740) or NS3 (ab13830) was from Abcam, Co. Ltd. The mAb to beta-actin (TA-09) was from Beijing ZSJQ-BIO Co. Ltd. Goat anti-mouse (sc-2005) and goat anti-rabbit (sc-2004) secondary antibodies were from Santa Cruz Biotechnology Inc.
Sofosbuvir psi 7977
Manufactured by MedChemExpress
Sofosbuvir (PSI-7977) is a nucleotide analog inhibitor of the hepatitis C virus (HCV) NS5B polymerase, which is essential for viral replication. It is used in research applications to study HCV biology and potential therapeutic interventions.
Automatically generated - may contain errors
2 protocols using sofosbuvir psi 7977
1
Evaluating HCV Inhibitor Compounds
2
Antiviral Compound Preparation Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Drugs were dissolved in DMSO and used at indicated concentrations. Sofosbuvir (PSI-7977) (Medchem Express), 10 μM; Daclatasvir (SelleckChem) 1nM.
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