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Signa hdxt

Manufactured by Siemens
Sourced in United States, Germany

The Signa HDxt is a magnetic resonance imaging (MRI) system developed by Siemens. It is designed to provide high-quality imaging results for a variety of medical applications. The Signa HDxt incorporates advanced imaging technologies to capture detailed anatomical information, enabling healthcare professionals to make informed decisions.

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5 protocols using signa hdxt

1

Multimodal MRI Analysis of Brain Structure

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All participants underwent an MRI scan of the brain (Siemens Avanto, n = 7; GE Discovery MR750, n = 14; Impax, n = 119; 3T Philips Ingenuity TF PET/MR system, n = 123; 1.5T GE Signa HDxt, n = 21; 3.0T GE Signa HDxt, n = 262; 1.5T Siemens Sonata, n = 27; 3T Toshiba Vantage Titan, n = 119; Vision, n = 1). The protocol included 3D T1-weighted images, 3D T2-weighted images, and 3D T2-weighted fluid-attenuated inversion-recovery (FLAIR) images.18 (link) Visual rating of medial temporal lobe atrophy (MTA) was performed on coronal T1-weighted images averaging scores for the left and right sides (range 0–4).28 (link) Posterior atrophy was rated using sagittal, axial, and coronal planes of T1 and FLAIR-weighted images averaging scores for the left and right sides (range 0–3).29 (link) Global cortical atrophy (GCA) was rated using axial FLAIR images (range 0–3).30 (link) The severity of white matter hyperintensities was determined on the FLAIR sequence using the Fazekas scale (range 0–3).31 (link) Lacunes were defined as deep lesions (3–15 mm) with CSF-like signal on all sequences. They were counted and dichotomized into absent (0) of present (≥1 lacune). Microbleeds were defined as small dot-like hypointense lesions on T2-weighted images. They were also counted and dichotomized into absent (0) or present (≥1 microbleed). An experienced neuroradiologist reviewed all scans.
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2

Cardiac MRI Protocol for Volumetrics and Iron

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The protocol (cardiac volumes, function, and cardiac/liver iron assessment) was imported and archived in each 1.5 T MRI scanner under the supervision of the physicist (R.B.)—centre 1: GE Healthcare Signa HDxt; centre 2: Siemens Avanto Syngo MR B17. The protocol included
An expert radiographer (L.M.) oversaw scanning, supported by local radiographers, who were trained to acquire images. Scan time was defined from the time stamp of the first image to the last image acquired.
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3

Gadoxetic Acid-Enhanced MRI Protocol

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Presurgery gadoxetic acid-enhanced MR images were retrieved from the Picture Archiving and Communication Systems of the participating centers. Patients fasted for 4–6 h before MR scanning. The scan was performed after injection of the contrast agent (0.025 mmol/kg gadoxetic acid, 15 ml, 7.04 g; Guangzhou Consun Pharmaceutical Co., Guangzhou, China) at a rate of 2 ml/s via an injector. The contrast agent was flushed with 20 ml saline injected at the same rate. The scanners used at the three medical centers were as follows: FAH-ZJU, 3.0-T MR scanner (Signa HDxt; GE Healthcare, Milwaukee, WI, USA); SLH, 1.5-T or 3.0-T MR scanner (Signa HDxt); and LSCH, 1.5-T MR scanner (Aera; Siemens Healthcare, Erlangen, Germany) or 3.0-T MR scanner (Ingenia; Philips Healthcare, Best, Netherlands).
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4

Breast MRI for Invasive Ductal and Lobular Carcinoma

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Patients with confirmed histopathological reports of IDC (30) and ILC (28) from the Duke breast cancer MRI data set of the cancer imaging archive (TCIA) were included in this study
18
,19 (link)
(underlying data).
20 (link)
Sample size for the study was calculated using the formula of sensitivity and specificity for diagnostic test accuracy based on sensitivity and specificity and area under the curve.
The MRI breast dataset (IDC and ILC) used for this study is publicly available online at
https://wiki.cancerimagingarchive.net/;
https://doi.org/10.7937/TCIA.e3sv-re93). The Duke breast cancer dataset is composed of a retrospectively collected cohort of 922 biopsy-confirmed invasive breast cancer patients from a single institution (Duke Hospital, Durham, North Carolina, USA) with preoperative MRI from January 1, 2000 to March 23, 2014. The images were acquired using 1.5 Tesla GE (Signa Excite, Signa HDxt) and Siemens (Avanto) MRI scanners. The mean age (years) of the patients with IDC and ILC was 48 ± 11.15 and 59 ± 11 years, respectively. Demographic characteristics are shown in
Table 1. Axial T1 dynamic post-contrast (DCE) sequence (gadolinium-based contrast of 15–20 ml) was performed using the image acquisition parameters listed in
Table 2.
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5

MRI Characteristics of Thecoma-Fibroma Tumors

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MRI examinations were performed on a 3.0-T unit (Signa HDxt, GE Healthcare) or a 1.5-T unit (Magnetom Vision; Siemens AG, Erlangen, Germany or Signa HDxt).
The MRI characteristics of each thecoma-fibroma tumor were recorded separately and included the following items: Lesion components (solid, cystic, solid with cystic components, or cystic with solid components), signal intensity on T2-weighted imaging (WI) (hypointensity, isointensity, or hyperintensity), and gadopentetate dimeglumine (Gd-DTPA) enhancement (mild, moderate or severe). The signal intensity of each lesion on T2WI was quantitatively compared with that of the uterine myometrium and iliopsoas muscle. On T2WI, the hypointensity and hyperintensity of the pelvic wall muscle and fat signals were similar. After the intravenous injection of contrast medium, the degree of lesion enhancement was graded as follows: Mild enhancement (less than the myometrium), moderate enhancement (similar to the myometrium), or severe enhancement (greater than the myometrium).
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