3 aminopyrazole

Manufactured by Merck Group

Sourced in United States

3-aminopyrazole is a chemical compound that serves as a versatile building block in the synthesis of various pharmaceutical and agrochemical products. It features a pyrazole ring structure with an amino group attached. 3-aminopyrazole is primarily used as an intermediate in the production of active pharmaceutical ingredients and other specialty chemicals.

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Lab products found in correlation

2 protocols using 3 aminopyrazole

Synthesis and Characterization of Lipid Nanoparticles

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Tetronic acid, myristic acid, palmitic acid, 3-aminopyrazole, 5-bromovanillin, triethylamine (Et₃N), thionyl chloride (SOCl₂), 4-dimethylaminopyridine (DMAP), ethyl acetate (EtOAc), benzene, hexanes, ethanol (EtOH), methanol (MeOH), dimethyl sulfoxide (DMSO), dimethylformamide (DMF), methylene chloride (CH₂Cl₂), sephadex G75, phosphate buffered saline (PBS), RPMI-1640, DMEM, fetal bovine serum (FBS), MTT reagent, porcine pancreas lipase and porcine liver esterase were purchased from Sigma-Aldrich or Fisher Scientific, USA. Chloroform solutions of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)2000] ammonium salt (DSPE-PEG2000) and 1,2-dipalmitoyl-snglycero-3-phosphocholine (DPPC) were purchased from Avanti Polar Lipids (Alabaster, USA). Lipophilic tracers DiO and DiI were purchased from Life Technologies, USA. Annexin V-FITC conjugate was ordered from Southern Biotech, USA.

Mikhalin A.A., Evdokimov N.M., Frolova L.V., Magedov I.V., Kornienko A., Johnston R., Rogelj S, & Tartis M.S. (2014). Lipophilic prodrug conjugates allow facile and rapid synthesis of high loading capacity liposomes without the need for post-assembly purification. Journal of liposome research, 25(3), 232-260.

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Synthesis and Characterization of Lipid-Based Nanoparticles

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3- aminopyrazole, 4- dimethylaminopyridine (DMAP), 5- bromovanillin, dimethyl sulfoxide (DMSO), dimethylformamide (DMF), ethanol (EtOH), methanol (MeOH), methylene chloride (CH₂Cl₂), MTT reagent, phosphate buffered saline (PBS), podophyllotoxin (P), tetronic acid, and triethylamine (Et3N) were purchased from Sigma-Aldrich or Fisher Scientific (Milwaukee, WI/Fairlawn,NJ). Chloroform solutions of 1,2-dipalmitoyl-sn-glycero-3-phophate (monosodium salt) (DPPA); 1,2-dipalmitoly-snglycero-3-phosphocholine (DPPC); 1,2-distearoyl-sn-glycerol-3-phosphoethanolamin-N-[methoxy(polyethylene glycol) -2000] ammonium salt (DSPE-PEG2000); and 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine-N-(polyethyleneglycol)-5000) (ammonium salt) (DSPE-PEG5000) were purchased from Avanti Polar Lipids (Alabaster, AL). COATSOME® FE-6060GL (DPPE-Glu) was purchased from NOF America Corporation.

Márquez M.G., Dotson R., Pias S., Frolova L.V, & Tartis M.S. (2020). Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery. Nanotheranostics, 4(1), 40-56.

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