Brilliance workspace portal

Manufactured by Philips

The Brilliance Workspace Portal is a computer-based platform designed for laboratory management and data integration. It serves as a central hub for organizing and accessing various laboratory resources and information.

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Lab products found in correlation

Brilliance ict, by Philips (1 mentions) Idose4, by Philips (1 mentions) Vue pacs, by Carestream (1 mentions) Iohexol, by GE Healthcare (1 mentions)

5 protocols using brilliance workspace portal

Detailed Airway Imaging Protocol with CT

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We used the image data of 65 subjects assessed in our previous study.8 (link) In brief, a multi-slice CT scanner (256 slices, Brilliance iCT; Philips Healthcare, Cleveland, OH, USA) was used. The CT scans were acquired with the following parameters: tube voltage: 120 kVp; tube current-time product: 200 mAs; detector configuration: 20×0.625 mm collimation with UHR mode; reconstruction section thickness; 0.67 mm, helical mode with 0.55 pitch; gantry rotation time: 0.4 seconds; display field of view: 200 mm. In order to reduce image noise, all images were reconstructed from UHR data using an interactive reconstruction algorithm (iDose4 (link); Philips Healthcare).13 (link)–15 (link) The patients were asked to inhale deeply and hold for several moments, after which the scans were obtained. The reconstructed data were transferred to a workstation (Brilliance™ Workspace Portal; Philips Healthcare) and then reconstructed into the curved MPR of the airway.

Kurashima K., Takaku Y., Hoshi T., Kanauchi T., Nakamoto K., Takayanagi N., Yanagisawa T., Sugita Y, & Kawabata Y. (2015). Lobe-based computed tomography assessment of airway diameter, airway or vessel number, and emphysema extent in relation to the clinical outcomes of COPD. International Journal of Chronic Obstructive Pulmonary Disease, 10, 1027-1033.

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Measuring Masticatory Muscle Cross-Sectional Area

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CSAs of the masseter and temporalis muscles (which reflect peak force) were measured using the planar mode for sectioning CT stacks, and the ‘region of interest’ tool for tracing outlines and measuring areas available on the Brilliance Workspace Portal (Philips v. 2.6.1.5). Masticatory muscle CSAs were measured following the method of Weijs and Hillen^{28 (link)} (Fig. 1). The muscle CSA was controlled for mandibular size using either mandibular centroid size (in GM analyses) or the geometric mean of the mandibular linear measurements (MGM - for analyses of anthropometric data; see statistical analysis section).Figure 1

Muscle cross-sectional area measurement following Weijs and Hillen^{28 (link)}. Masseter (1) area was estimated by tracing it on the CT scan sectioned 3 cm ventro-cranially to the jaw angle, 30° relative to the Frankfurt horizontal plane. Temporalis (2) area was measured one cm cranially to the zygomatic arch, parallel to the Frankfurt horizontal plane.

Sella-Tunis T., Pokhojaev A., Sarig R., O’Higgins P, & May H. (2018). Human mandibular shape is associated with masticatory muscle force. Scientific Reports, 8, 6042.

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Mandibular Geometry Analysis from CT Scans

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All linear and CSA measurements were controlled for general mandibular size, as expressed by its geometric mean (MGM—mandibular geometric mean). The latter was calculated based on a set of six linear measurements: ramus length and width, mandibular body length, gonial width, coronoid length, andbigonial breadth, following the methods described by Sella Tunis et al. [28 (link)]. All measurements were taken directly from the CT scans using the Brilliance Workspace Portal (Philips v. 2.6.1.5, Philips, Amsterdam, Netherlands). The square roots of the chin and symphysis CSAs were divided by the MGM, following the principles presented in Jungers et al. [29 (link)].

Sella Tunis T., Hershkovitz I., May H., Vardimon A.D., Sarig R, & Shpack N. (2020). Variation in Chin and Mandibular Symphysis Size and Shape in Males and Females: A CT-Based Study. International Journal of Environmental Research and Public Health, 17(12), 4249.

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Perfusion CT Brain Imaging Protocol

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Perfusion acquisitions were realized during the first control head CT scan, using a LightSpeed multi-detector row CT system (GE Medical Systems, Milwaukee, WI). Scanning was initiated 5 sec after injection of 50 mL of iohexol (300 mg/mL of iodine; GE Healthcare Europe, Glattbrugg, Switzerland), perfused at a rate of 5 mL/sec with the following parameters: 80 kV, 240 mAs, 0.4 rotations/sec, total duration of 50 sec. The series evaluated 16 adjacent 5-mm-thick sections of brain parenchyma. A dedicated software (Brilliance Workspace Portal^®; Philips Medical Systems, Cleveland, OH), which employs the central volume principle using deconvolution to measure mean transit time (MTT), was used. Cerebral blood volume (CBV) was calculated from the time-enhancement curves, and global CBF was derived from the equation: CBF = CBV/MTT. Three-dimensional reconstruction was processed with Carestream Vue PACS^® (Carestream Health, Rochester, NY) using a series of the thin-slice enhanced brain CT. Regions of interest (ROI) were selected in line with our previous studies providing an accurate quantitative assessment of CBV, MTT, and CBF of each hemisphere.^{14 (link),15 (link)} A global value of CBV, MTT, and CBF was calculated by averaging values from right and left hemispheres. Post-processing of PCT data was performed by an experienced neuroradiologist who was blinded to CMD variables.

Quintard H., Patet C., Zerlauth J.B., Suys T., Bouzat P., Pellerin L., Meuli R., Magistretti P.J, & Oddo M. (2016). Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio. Journal of Neurotrauma, 33(7), 681-687.

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Quantifying Aortic Calcification with CT

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Abdominal Aorta Calcium Score was obtained using Philips Brilliance Workspace Portal, Version 6.02, by Philips Medical Systems Netherlands BV. Circular regions-of-interest (ROI) were manually drawn around the aortic wall on each axial unenhanced image containing visible calcifications, defined as CT density greater than or equal to 130 Hounsfield units (HU), from the level of the celiac axis to aortic bifurcation, taking care not to include any vertebral bone area. The 130 HU threshold is recommended by the software vendor and is commonly used for CT assessment of arterial calcification.^{[25 (link)–27 (link)]} The postprocessing software then summed the individual calcification areas and densities, calculating total calcification area and Agatston score (Fig. 1).

Goldenberg L., Saliba W., Hayeq H., Hasadia R, & Zeina A.R. (2018). The impact of abdominal fat on abdominal aorta calcification measured on non-enhanced CT. Medicine, 97(49), e13233.

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