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Blx 312 uv crosslinker

Manufactured by Vilber
Sourced in France

The BLX-312 UV crosslinker is a laboratory equipment designed for UV-based crosslinking applications. It utilizes 312 nm UV light to facilitate covalent bond formation between molecules. The device incorporates a microprocessor-controlled timer and adjustable UV intensity settings to provide precise control over the crosslinking process.

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2 protocols using blx 312 uv crosslinker

1

UVB-Induced Skin Damage Mitigated by 17-Oxo-DHA

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Female SKH1-Hrhr mice (5–6 weeks of age) were randomly divided into three groups (n = 7 per group). The mice were irradiated with UVB (180 mJ/cm2) using the Biolink BLX-312 UV crosslinker (Vilber Lourmat; Marne-la-Vallée, Paris, France) three times a week for 26 weeks. 17-Oxo-DHA (20 nmol) dissolved in 200 μL of acetone was topically applied onto the dorsal skin of mice 30 min prior to each UVB exposure. Mice were euthanized and their skin tissues were collected for adequate analysis.
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2

UVB-Induced Hair Roughness in Mice

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The mice were randomly assigned to different groups and carefully prepared by shaving hair using hair clippers from their backs to ensure that no skin trauma occurred during the process. To induce roughness in newly growing hair, UVB irradiation was applied using a 312-nm lamp (BLX312 UV Crosslinker; Vilber Lourmat, Marne-la-Vallée, France) after sedation of mice. The dosages varied from 0 to 150 mJ/cm2 per exposure (0, 40, 60, 80, and 150 mJ/cm2) and were administered over a period of 5 days (Figure 4a). Irradiation was repeatedly administered for consecutive 5 days with a 24-h interval. The total accumulative irradiation dose was each 0, 200, 300, 400, 600 mJ/cm2.
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