Baicalin

Manufactured by Chengdu Herbpurify

Sourced in China

Baicalin is a compound extracted from the root of the Scutellaria baicalensis plant. It is a key ingredient used in the production of various herbal and pharmaceutical products. Baicalin is known for its antioxidant and anti-inflammatory properties. The precise function and intended use of Baicalin may vary depending on the specific application or product formulation.

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Lab products found in correlation

4 protocols using baicalin

Quantification of Flavonoids and Polyphenols

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Chromogenic substrate S-2238 was purchased from Chromogenix (Milan, Italy); bovine thrombin and argatroban were purchased from Sigma-Aldrich (St. Louis, MO, USA). The phosphate buffer saline (PBS) (pH 7.2-7.4, 0.01 M) and dimethyl sulfoxide (DMSO) were purchased from Solarbio (Beijing, China). Standard substance of galangin, kaempferol, astragaline, fisetin, quercetin, quercitrin, isoquercitrin, rutin, isorhamnetin, isorhamnetin-3-O-neohespeidoside, typhaneoside, myricetin, myricitrin, baicalein, baicalin, wogonin, wogonoside, hispidulin, scutellarein, genkwanin, hydroxygenkwanin, luteolin, luteoloside, 6-methoxyluteolin, dihydroquercetin, dihydromyricetin, naringenin, naringin, narirutin, hesperetin, hesperidin, neohesperidin, L-epicatechin, (-)-epigallocatechin, (-)-epicatechin gallate, proanthocyanidin B1 with 98% purity on the basis of HPLC analysis were obtained from Chengdu Herbpurify Co., Ltd. (Chengdu, China). Herbacetin and morin were obtained from Chengdu Must Bio-Technology Co., Ltd. (Chengdu, China). chrysin, apigenin, diosmetin and kaempferol-7-O-β-d-glucopyranoside were purchased from Chengdu Desite Bio-Technology Co., Ltd. (Chengdu, China).

Wang X., Yang Z., Su F., Li J., Boadi E.O., Chang Y.X, & Wang H. (2020). Study on Structure Activity Relationship of Natural Flavonoids against Thrombin by Molecular Docking Virtual Screening Combined with Activity Evaluation In Vitro. Molecules, 25(2), 422.

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Phytochemical Analysis of Medicinal Compounds

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QGC (provided by the laboratory of Affiliated Hospital of Southwest Medical University). Sodium Uric Acid Crystals (5 g, Rohn Reagent, Lot No. RH389360). Colchicine (100 mg/stem, Rohn Reagent, Lot No. RH341403). Maltol (Purity ≥98 %, Sichuan Weikeqi Biological Technology Co.,Ltd., Lot No. wkq22070114). Cafferic acid (Purity >98 %, Ltd，Lot No. DSTDE001301) and Catechin (Purity >99.87 %, Lot No. DSTDE000102) are from Chengdu Desite Biotechnology Co., Ltd. β-Sitosterol (Purity >98 %, Chengdu Ruifensidan Biotechnology Co., Ltd, Lot No. G00202005008), Ferulic acid (Lot No. RFS-A00211812016), Luteolin (Lot No. RFS-M00702004028), Baicalin (Lot No. RFS-H01811804026), Berberine (Lot No. RFS-Y03511811015), Quercetine (Lot No. RFS-H00911812016), Apigenin (Lot No. RFS-Q00211801029), Isorhamnetin (Lot No. RFS-Y03911811003) and Tangeritin (Lot No. RFS-J02202008018) all have purity >98 %, which were from Chengdu Herbpurify Co., Ltd. Kaempferol (Purity >98 %, Lot No. MSUT-13121112) and Neochlorogenic acid (Purity >99.40 %, Lot No. MSUT-21070910) were from Chengdu MUST Bio-Technology Co., Ltd. Mollugin (Purity >99.90 %, Chengdu MUST Bio-Technology Co., Ltd, Lot No. MSUT-21060211).

Xiang G., Yang L., Qin J., Wang S., Zhang Y, & Yang S. (2024). Revealing the potential bioactive components and mechanism of Qianhua Gout Capsules in the treatment of gouty arthritis through network pharmacology, molecular docking and pharmacodynamic study strategies. Heliyon, 10(10), e30983.

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Baicalin Extraction and Purification

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Baicalin was purchased from Chengdu Herbpurify Co., Ltd (Chengdu, China, purity: 99%). Phosphate buffer solutions (PBS) were obtained from Solarbio Life Science. NaOH was purchased from Aladdin company (Shanghai, China). Na₂B₄O₇ was purchased from Damas-beta company (Shanghai, China). The chemicals were used as received without further purification.

Wang Z.Z., Jia Y., Wang G., He H., Cao L., Shi Y., Miao M, & Li X.M. (2022). Dynamic covalent hydrogel of natural product baicalin with antibacterial activities. RSC Advances, 12(14), 8737-8742.

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Quantification of Bioactive Compounds from Traditional Chinese Herbs

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Paeoniflorin, baicalin, scutellarein, liquiritigenin, baicalein, glycyrrhizic acid, wogonin, and oroxylin A were purchased from Chengdu Herbpurify Co., Ltd. (Sichuan, China). glycyrrhizic acid ammonium salt and norwogonin were purchased from ChemFaces (China). All other reagents and solvents were of high performance liquid chromatography (HPLC) grade. Deionized water was purified using a Milli-Q system (Millipore, Bedford, MA, United States). Scutellaria baicalensis Georgi (Hebei Province), Glycyrrhiza uralensis Fisch (Inner Mongolia of China), Paeonia lactiflora Pall (Anhui Province), and Ziziphus jujuba Mill (Henan Province) were authenticated by Dr. Ehu Liu (State Key Laboratory of Natural Medicines, China Pharmaceutical University, China).

Dai X.M., Cui D.N., Wang J., Zhang W., Zhang Z.J, & Xu F.G. (2018). Systems Pharmacology Based Strategy for Q-Markers Discovery of HuangQin Decoction to Attenuate Intestinal Damage. Frontiers in Pharmacology, 9, 236.

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