K562 cells and K562/ADR cells were purchased from RIKEN Innovation Co., Ltd. Doxorubicin was from Fresenius Kabi (Bangkok, Thailand) Ltd. Curcumin was purchased from Nacalai Tesque (Kyoto, Japan), pirarubicin (4-Q-tetrahydropyraylDoxorubicin) and verapamil were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit monoclonal anti-P-gp IgG was purchased from Boster Biological Technology, while rabbit polyclonal anti-human GAPDH IgG anti-GAPDH was purchased from Santa Cruz Biotechnology, Santa Cruz, CA, USA. The apoptosis kit was BioLegend (Santa Cruz, CA, USA).
Curcumin
Manufactured by Nacalai Tesque
Sourced in Japan
Curcumin is a yellow-colored chemical compound extracted from the rhizome of the turmeric plant. It is a key component in various lab equipment and is commonly used as a colorant, antioxidant, and for its potential anti-inflammatory properties.
Automatically generated - may contain errors
Lab products found in correlation
Verapamil, by Merck Group (1 mentions)
Doxorubicin, by Fresenius (1 mentions)
Pirarubicin, by Merck Group (1 mentions)
Palmitic acid, by Nacalai Tesque (1 mentions)
Quercetin, by Merck Group (1 mentions)
Glutamine, by Nacalai Tesque (1 mentions)
Sucrose, by Nacalai Tesque (1 mentions)
Pyruvate, by Nacalai Tesque (1 mentions)
Apigenin, by Tokyo Chemical Industry (1 mentions)
Hesperidin, by Extrasynthese (1 mentions)
Emodin, by Tokyo Chemical Industry (1 mentions)
Cyanidin chloride, by Extrasynthese (1 mentions)
Genistein, by LKT Laboratories (1 mentions)
Formaldehyde solution, by Avantor (1 mentions)
Antibiotic antimycotic, by Thermo Fisher Scientific (1 mentions)
Resveratrol, by Tokyo Chemical Industry (1 mentions)
Ascorbic acid, by Fujifilm (1 mentions)
Rutin, by Nacalai Tesque (1 mentions)
Sesamin, by Cayman Chemical (1 mentions)
Epigallocatechin 3 gallate, by Cayman Chemical (1 mentions)
4 protocols using curcumin
1
Curcumin Enhances Doxorubicin Sensitivity in Drug-Resistant Leukemia Cells
2
Phytochemicals Sourcing and Preparation
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Oleic acid and resveratrol were purchased from Wako Pure Chem. Ind., Ltd. (Tokyo, Japan). Phenylalanine was from Nippon Rika (Tokyo, Japan). Quercetin was obtained from Sigma-Aldrich (St. Louis, MO). Apigenin and emodin were from Tokyo Chemical Industry (Tokyo, Japan). Cyanidin chloride and hesperidin were from Extrasynthese (Genay, France). Ferulic acid and genistein were from LKT Laboratories (St. Paul, MN). Dipeptidyl peptidase (DPP) IV inhibitor was from Calbiochem (San Diego, CA). Palmitic acid, glutamine, glucose, sucrose, chlorogenic acid hemihydrates, (–)-epigallocatechin-3-gallate, curcumin and pyruvate were obtained from Nacalai Tesque (Kyoto, Japan). All other chemicals were of the highest grade commercially available.
3
In Vitro Evaluation of EC-Curcumin Efficacy
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Eucheuma cottonii (EC) was provided by a seaweed farm in Sabah (Famous Alpine Sdn. Bhd, Sabah, Malaysia). Curcumin was purchased from Nacalai Tesque, Inc. (Kyoto, Japan). Dextran sulfate sodium (DSS, MW ~40.000 Da) was purchased from Tokyo Chemical Industry (Tokyo, Japan). Tumor necrosis factor (TNF)-α (Cat. No. ARG80206), interleukin (IL)-6 (Cat. No. ARG80199), IL-1β (Cat. No. ARG80196), and IL-10 (Cat. No. ARG80200) ELISA kits were purchased from Arigo Biolaboratories Corporation (Hsinchu, Taiwan). Formaldehyde solution (4%) was purchased from Avantor Performance Materials, Inc. (Pennsylvania, U.S.A.). Dulbecco’s modified Eagle’s medium-low glucose (DMEM-L) and Dulbecco’s phosphate buffered saline (PBS) powders were purchased from Sigma Aldrich (Missouri, U.S.A). Antibiotic-Antimycotic (15240–062) was purchased from Gibco Life Technologies (Massachusetts, U.S.A.).
4
Standardized Phytochemical Compound Acquisition
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Ferulic acid (99%) was purchased from Sigma Aldrich (St. Louis, MO, USA). Ascorbic acid and quercetin (≤100%) were purchased from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). Caffeic acid (≥98%), curcumin (100%), hesperidin (90%), rutin (95.0–101.5%), and triiodothyronine (T3) were purchased from Nacalai Tesque, Inc. (Kyoto, Japan). Gallic acid (≥98%), chlorogenic acid (≥95%), ellagic acid (≥95%), sesamin (≥95%), epigallocatechin-3-gallate (≥96%), genistein (≥98%), daidzein (≥95%), luteolin (≥98%), theaflavin (≥98%), isoquercetin (98%), and morin (100%) were purchased from Cayman Chemical Company (Ann Arbor, MI, USA). Resveratrol (>99.0%), fisetin (>96.0%), isorhamnetin (>95.0%), and troxerutin (90%) were purchased from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Cyanidin chloride (99%) was purchased from Nagara Science Co. Ltd. (Gifu, Japan). Apigenin (≥98%) was purchased from LKT Laboratories, Inc. (St. Paul, MN, USA). Kaempferol (98%), myricetin (98%), and naringin (98%) were purchased from BDL Pharmatech Ltd. (Shanghai, China). Hyperoside (90–100%) was purchased from Toronto Research Chemicals Inc. (Toronto, ON, Canada). Neohesperidin (≥98%) was purchased from Chem-Impex International, Inc. (Wood Dale, IL, USA). All other chemicals were commercially available and had the highest possible purity.
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