Coda ht8

Manufactured by Kent Scientific

Sourced in France, United States

The CODA-HT8 is a high-throughput non-invasive blood pressure monitoring system. It utilizes the oscillometric method to measure blood pressure in small laboratory animals such as mice and rats. The system is designed to provide reliable and accurate blood pressure data for research purposes.

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Lab products found in correlation

Ecgtunnel, by EMKA Technologies (1 mentions) Coda high throughput noninvasive blood pressure system, by Kent Scientific (1 mentions)

4 protocols using coda ht8

Hypertension Progression in Aging Rats

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The rats were kept in a conscious and immobilized state to ensure blood pressure sensors were fixed to the tail, and were maintained at a suitable temperature (30-35˚C) and level of awareness for the duration of the experiment. The systolic and diastolic blood pressure levels of the rats in each group were monitored every 2 weeks, using a blood pressure analysis system (CODA-HT8; Kent Scientific Corp), from 14-weeks-old to 48-weeks-old.

Wu H., Zhai Y., Yu J., Wei L, & Qi X. (2024). Transcriptome and proteome analyses reveal that upregulation of GSTM2 by allisartan improves cardiac remodeling and dysfunction in hypertensive rats. Experimental and Therapeutic Medicine, 27(5), 220.

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Cardiovascular Assessment in Rats

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At week 5 of the experiment, electrocardiogram (heart rate, voltage and time parameters (P wave and QRST complex), and changes in the isoelectric line) and blood pressure (systolic, diastolic, mean arterial pressure, blood flow velocity, tail blood volume, and heart rate) parameters in rats were registered non-invasively using the ecgTUNNEL (emka TECHNOLOGIES, Paris, France) and CODA-HT8 (Kent Scientific, Torrington, USA) instruments, respectively.

Minigaliyeva I.A., Klinova S.V., Sutunkova M.P., Ryabova Y.V., Valamina I.E., Shelomentsev I.G., Shtin T.N., Bushueva T.V., Protsenko Y.L., Balakin A.A., Lisin R.V., Kuznetsov D.A., Katsnelson B.A, & Toropova L.V. (2023). On the Mechanisms of the Cardiotoxic Effect of Lead Oxide Nanoparticles. Cardiovascular Toxicology, 24(1), 49-61.

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Studying Hypertension in Rat Model

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The systolic blood pressure (sBP) of the rats was determined using the tail-cuff method with the CODA high-throughput non-invasive blood pressure system (Product # CODA-HT8, Kent Scientific Corporation). The arterial pressures were measured at 0, 2, 4, 6, and 8 weeks after the 2K1C surgery. Eight weeks later, some of the hypertensive rats received t-AUCB (1 mg/kg/day) in their drinking water for 1 week. Thereafter, the sBP of the 3 group rats (Sham, 2K1C, and 2K1C + t-AUCB) were evaluated at the end of week 9.

Wang X., Han W., Zhang Y., Zong Y., Tan N., Zhang Y., Li L., Liu C, & Liu L. (2022). Soluble Epoxide Hydrolase Inhibitor t-AUCB Ameliorates Vascular Endothelial Dysfunction by Influencing the NF-κB/miR-155-5p/eNOS/NO/IκB Cycle in Hypertensive Rats. Antioxidants, 11(7), 1372.

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Non-invasive Blood Pressure Monitoring

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Blood pressure and heart rate were measured daily by the non-invasive tail-cuff method (CODA-HT8, Kent Scientific Corporation, CT, USA) following the manufacturer’s instructions. For all groups, 15~20 measurements were taken for each mouse, and the averages of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP), and heart rate were then calculated.

Nguyen M.C, & Ryoo S. (2016). Intravenous administration of piceatannol, an arginase inhibitor, improves endothelial dysfunction in aged mice. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(1), 83-90.

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