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Xanthohumol from hop

Manufactured by Merck Group
Sourced in United States

Xanthohumol is a naturally occurring compound derived from hop plants. It is an active compound with antioxidant properties. The core function of Xanthohumol is to serve as a research tool for scientific investigations, though its potential applications are still under study.

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2 protocols using xanthohumol from hop

1

Purification of Bioactive Chalcones

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2′-hydroxy-4,4′,6′-trimethoxychalcone (HCH) with ≥98% purity, cardamonin (CA) with ≥98% purity, xanthohumol from hop (Humulus lupulus) (XN) with ≥96% purity, isobavachalcone (IBC) with ≥98% purity and licochalcone A (LIC) with ≥96% purity were purchased from Sigma-Aldrich (Saint Louis, MO, USA). Methanol, ethanol, ethylene glycol, DMSO, acetonitrile, THF and n-hexane were of analytical grade.
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2

Quantification of Bitter Acids and Xanthohumol in Hops

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Dichloromethane (CH 2 Cl 2 ) and anhydrous sodium sulfate were purchased from Sigma-Aldrich (Milan, Italy). Toluene was purchased from Carlo Erba (Milan, Italy). Ultra-pure water was in-house produced by using a Milli-Q-System (Millipore, Bedford, MA, USA). Methanol (HPLC grade) was purchased from Sigma-Aldrich. Bitter acids mixture standard (international calibration extract, ICE-3) was from Labor Veritas Co. (Zürich, Switzerland). The standard mixture contained α-acids with 13.88% of cohumulone and 30.76% of n-humulone + adhumulone, and β-acids with 13.44% of colupulone and 10.84% of n-lupulone + adlupulone. Xanthohumol from hop (Humulus lupulus L.) ≥ 96% HPLC-grade standard was purchased from Sigma-Aldrich. Trolox (6-hydroxy-2,5,7,8tetramethylchroman-2-carboxylic acid), DPPH (2,2-diphenyl-1-picrylhydrazyl free radical) and acetone, were purchased from Sigma-Aldrich, St. Louis.
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