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4 protocols using 3.0t tim trio or prisma scanner

1

PET and MRI Imaging Protocols Across Cohorts

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PET images were acquired using a Biograph mCT PET/CT scanner (Siemens Medical Solutions) in Seoul [11 (link)]; Discovery and Discovery MI PET scanners (GE medical systems) in BioFINDER 1 and 2, respectively [5 (link), 6 (link)]; a Biograph 6 Truepoint PET/CT scanner (Siemens Medical Solutions) for UCSF patients [18 (link)], a Siemens High-Resolution Research Tomograph (HRRT) scanner in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts. All PET data were locally reconstructed into 4 × 5-min frames for the 80–100-min ([18F]flortaucipir) and 70–90-min ([18F]RO948) intervals post-injection. MR images were acquired on a 3.0T Discovery MR750 scanner (GE medical systems) in Seoul [11 (link)], 3.0T Tim Trio or Skyra scanner (Siemens Medical Solutions) in BioFINDER [5 (link), 6 (link)], a 3.0T Tim Trio or Prisma scanner (Siemens Medical Solutions) at UCSF [18 (link)], a 3.0 Tim Trio scanner (Siemens Medical Solutions) in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts.
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2

Multimodal Neuroimaging Protocols in Neurodegenerative Research

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PET images were acquired using a Biograph mCT PET/CT scanner (Siemens Medical Solutions) in Seoul [11 (link)]; Discovery and Discovery MI PET scanners (GE medical systems) in BioFINDER 1 and 2, respectively [5 , 6 (link)]; a Biograph 6 Truepoint PET/CT scanner (Siemens Medical Solutions) for UCSF patients [18 (link)], a Siemens High-Resolution Research Tomograph (HRRT) scanner in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts. All PET data were locally reconstructed into 4 × 5-min frames for the 80–100-min ([18F]flortaucipir) and 70–90-min ([18F]RO948) intervals post-injection. MR images were acquired on a 3.0T Discovery MR750 scanner (GE medical systems) in Seoul [11 (link)], 3.0T Tim Trio or Skyra scanner (Siemens Medical Solutions) in BioFINDER [5 , 6 (link)], a 3.0T Tim Trio or Prisma scanner (Siemens Medical Solutions) at UCSF [18 (link)], a 3.0 Tim Trio scanner (Siemens Medical Solutions) in PREVENT-AD [15 (link)], and across multiple scanners in the multi-center ADNI [27 (link)] and Avid Radiopharmaceuticals [7 (link)] cohorts.
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3

Multi-center PET and MRI Imaging Protocol

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The PET images were acquired using a Biograph micro-CT PET/CT scanner (Siemens Medical Solutions) in the Memory Disorder Clinic of Gangnam Severance Hospital, Discovery 690 PET scanner (GE Medical Systems) in the BioFINDER study, and a Biograph 6 Truepoint PET/CT scanner (Siemens Medical Solutions) for UCSF patients. The PET data were locally reconstructed into 4- × 5-minute frames for the 80- to 100-minute interval after injection.15 (link),24 (link),25 (link) The MRIs were acquired on a 3.0-T Discovery MR750 scanner (GE Medical Systems) in the Memory Disorder Clinic of Gangnam Severance Hospital, 3.0-T Tim Trio or Skyra scanner (Siemens Medical Solutions) in the BioFINDER study, and a 3.0-T Tim Trio or Prisma scanner (Siemens Medical Solutions) at UCSF.
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PET/MRI Imaging Protocols for Neurological Disorders

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The PET images were acquired using a Biograph micro-CT PET/CT scanner (Siemens Medical Solutions) in the Memory Disorder Clinic of Gangnam Severance Hospital, Discovery 690 PET scanner (GE Medical Systems) in the BioFINDER study, and a Biograph 6 Truepoint PET/CT scanner (Siemens Medical Solutions) for UCSF patients. The PET data were locally reconstructed into 4- × 5-minute frames for the 80- to 100-minute interval after injection.15 (link),24 (link),25 (link) The MRIs were acquired on a 3.0-T Discovery MR750 scanner (GE Medical Systems) in the Memory Disorder Clinic of Gangnam Severance Hospital, 3.0-T Tim Trio or Skyra scanner (Siemens Medical Solutions) in the BioFINDER study, and a 3.0-T Tim Trio or Prisma scanner (Siemens Medical Solutions) at UCSF.
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