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Omnipaque 350 mg ml iohexol

Manufactured by GE Healthcare
Sourced in Norway, United States

Omnipaque 350 mg/mL (Iohexol) is a contrast agent used in diagnostic imaging procedures. It is a sterile, aqueous, radiopaque solution containing iohexol, a nonionic, water-soluble x-ray contrast medium.

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2 protocols using omnipaque 350 mg ml iohexol

1

Dual-Energy CT Scanning Protocols

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All patients were scanned in a second-generation multi-detector CT (Revolution CT ES, GE Healthcare, Milwaukee, Brookfield, WI, USA). For group A, scanning parameters were as follows: dual-energy helical scanning with 80/140 peak kV (kVp) fast switching with an automatic exposure control (GSI Assist, GE Healthcare, Milwaukee, WI, USA) and a noise index of 13, rotation time of 0.5 s, pitch of 0.992, slice thickness of 3 mm, and beam width of 80 mm [18 (link)]. For group B, conventional non-contrast images were acquired with 120 kVp, AutomA function (range: 80–600 mA) with a noise index of either 13 or 18, rotation time of 0.5 s, helical pitch of 0.992, slice thickness of 3 mm, and beam width of 80 mm. Dual-energy scan parameters for group B were identical to group A aside from the mA mode, which was set to 200 mA with GSI Assist.
Omnipaque 350 mg/mL (Iohexol, GE Healthcare, Oslo, Norway) was used for the contrast-enhanced DECT scans. Contrast was administered through an 18-gauge plastic cannula in the antecubital vein. Contrast volume was either 100 mL or 130 mL for a patient between 60–90 kg at a flowrate of 4 mL/s. The delay for arterial and venous phase was either 7 s or 15 s and 45 s or 55 s, respectively, following HU threshold triggering within the aorta set to 100 and 120 HU.
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2

Comprehensive CT Imaging of Abdomen and Pelvis

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All patients were scanned in a second-generation 256-slice CT (Revolution CT; GE Healthcare, Chicago, IL, USA). For the conventional non-contrast and arterial phase scan a kVp of 120 was used with a tube current between 80 and 600 mA (SmartmA) and a noise index of 13 and 14, respectively. For the venous phase acquisition, fast kV-switching (80/140 kV) was applied using Gemstone Spectral Imaging (GSI) Assist (GE Healthcare, Chicago, IL, USA) with a noise index of 14. Rotation speed, pitch, and beam width for all phases were set to 0.5 s, 0.992, and 80 mm, respectively.
Omnipaque 350 mg/mL (Iohexol, GE Healthcare, Chicago, IL, USA) was administered through an 18-gauge plastic cannula in the antecubital vein. Contrast volume was 1.4 mL/kg at a flow rate of 4 mL/s. The arterial and venous phase delay were set to 7 and 45 s following HU threshold triggering within the aorta at 100 HU.
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