in this study. The protocol for these experiments was reviewed and approved by the
committee of Ethics of Animal Experiments of Fukuoka Dental College (#18008). All mouse
experiments were performed in accordance with the guidelines of the committee of Ethics of
Animal Experiments of Fukuoka Dental College. C57BL/6N (B6) mice (CLEA Japan, Shizuoka,
Japan) and IL-17A-GFP reporter mice (The Jackson Laboratory, Bar Harbor, ME, USA) were
kept under specific pathogen-free conditions in the animal facility of Fukuoka Dental
College. All animals were kept in a controlled environment with a 12 h light/dark cycle
(lights on at 7:00 am). Mice were group housed (2–5 per cage) and given access to food and
water ad libitum.