The mean PS (nm) and PDI of the different DZ-loaded prepared cubosomal dispersions were detected using Zeta Seizer (Malvern Instrument Ltd., Worcestshire, UK), within a detection limit of 0.1–2000 µm. All samples were prepared by dilution (100 times) of cubosomal dispersion with deionized water before measurement (Jin et al., 2013 (link); Matloub et al., 2018 (link)).
Zeta seizer
Manufactured by Malvern Panalytical
Sourced in United Kingdom
The Zeta Sizer is a laboratory instrument used for measuring the size and charge of particles in a liquid suspension. It determines the particle size distribution and zeta potential, which is a measure of the surface charge of the particles. The Zeta Sizer provides accurate and reliable data to support research, development, and quality control applications.
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Lab products found in correlation
4 protocols using zeta seizer
1
Cubosomal Nanoparticle Characterization
2
Characterizing Encapsulated Powder Properties
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The moisture content of the capsules was determined by placing them in an oven at 105 ± 2°C until they attained a constant weight. The surface electrical charge of the capsules (zeta potential) was determined by using a Zeta seizer (Malvern Ltd., Malvern, UK). The volume mean diameter of the microcapsules was measured by using a particle seizer (Malvern Ltd., Malvern, UK).
The water activity of the powders produced by the LabMaster was determined (LabMaster.aw, Novasina, Switzerland).
The water activity of the powders produced by the LabMaster was determined (LabMaster.aw, Novasina, Switzerland).
3
Characterization of Nanomaterial Morphology
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The morphology and structure of the products were characterized using a SEM (S-4800) and a TEM (JEOL JEM-2100F) at accelerating voltages of 5 kV and 200 kV, respectively. The pore-size distribution of the products was determined by dynamic light scattering (DLS) using a Malvern Zeta Seizer instrument. N2 adsorption-desorption isotherms were measured using a Micromeritics ASAP 2020 M porosity analyzer. The samples were outgassed at 573 K for at least 2 h in a vacuum. The Brunauer-Emmett-Teller (BET) and Barrett-Joyner-Halenda (BJH) methods were used to determine pore volume, pore size and the surface areas of the samples.
4
Characterizing DOXY-Loaded Polymeric Nanoparticles
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The particle size, zeta potential (ZP), and polydispersity index (PDI) of all prepared DOXY-PNPs were measured using a zeta seizer (Malvern Instruments Ltd., Malvern, UK) [69 (link)]. Each sample of DOXY-PNPs was diluted with distilled water before analysis [70 (link),71 (link)].
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