N boc diethanolamine

The triblock co-polymer Poloxamer^® 407 (P407, poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide), PEO-PPO-PEO, ${\overline{M}}_n$ 12,600 Da, 70% w/w PEO), the aliphatic diisocyanate 1,6-hexamethylene diisocyanate (HDI), the catalyzer dibutyltin dilaurate (DBTDL) and the chain extender N-Boc diethanolamine were purchased from Merck (Milan, Italy). Prior to the synthesis, P407 was dried under dynamic vacuum at 100 °C for 8 h and then, cooled down to 40 °C under static pressure condition (200 mbar) until use, HDI was distilled under reduced pressure, N-Boc diethanolamine was kept at room temperature (RT) under vacuum in a desiccator, and 1,2-dichloroethane (DCE) was anhydrified over activated molecular sieves (3Å, Merck, Milan, Italy) under nitrogen atmosphere overnight. All solvents were purchased from Carlo Erba Reagents (Milan, Italy) in analytical grade and used as received if not further specified.