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Peg b pla

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PEG-b-PLA is a biodegradable and biocompatible copolymer consisting of polyethylene glycol (PEG) and polylactic acid (PLA). It is commonly used in the development of drug delivery systems, tissue engineering applications, and other biomedical research areas.

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Lab products found in correlation

Purified rat igg, by MP Biomedicals (2 mentions) Hypromellose, by Merck Group (1 mentions)

2 protocols using peg b pla

1

Antibody-Loaded Polymeric Nanoparticles

Cited 1 time
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Dodecyl-modified (hydroxypropyl)methyl cellulose (HPMC-C12, made from USP-grade HPMC (hypromellose, Sigma-Aldrich)) and poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) block copolymers were synthesized as previously described; PEG-b-PLA nanoparticles (NPs) were assembled by nanoprecipitation as previously described.27,28,42 (link) Unless otherwise stated, all chemicals were obtained from Sigma-Aldrich. Purified rat IgG was obtained from MP Biomedicals as a lyophilized powder. The Centi-C10 antibody against SARS-CoV-2 was generously provided by Dr. Sawsan Youssef and Dr. Jacob E. Glanville at Centivax.
Kasse C.M., Yu A.C., Powell A.E., Roth G.A., Liong C.S., Jons C.K., Buahin A., Maikawa C.L., Zhou X., Youssef S., Glanville J.E, & Appel E.A. (2023). Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot. Biomaterials Science, 11(6), 2065-2079.
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2

Synthesis and Characterization of PEG-b-PLA Nanoparticles

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Dodecyl-modified (hydroxypropyl)methyl cellulose (HPMC-C12, made from USP-grade HPMC (hypromellose, Sigma-Aldrich)) and poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA) block copolymers were synthesized as previously described; PEG-b-PLA nanoparticles (NPs) were assembled by nanoprecipitation as previously described.27 ,28 ,42 Unless otherwise stated, all chemicals were obtained from Sigma-Aldrich. Purified rat IgG was obtained from MP Biomedicals as a lyophilized powder. The Centi-C10 antibody against SARS-CoV-2 was generously provided by Dr. Sawsan Youssef and Dr. Jake Glanville at Centivax.
Kasse C.M., Yu A.C., Powell A.E., Roth G.A., Liong C.S., Jons C.K., Buahin A., Maikawa C.L., Zhou X., Youssef S., Glanville J.E, & Appel E.A. (2023). Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot. Biomaterials Science, 11(6), 2065-2079.
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