MR acquisitions were all performed on 2 imaging machines (MRI) from the same manufacturer (General Electric®, Milwaukee, USA): Optima MR450w 1.5T and Discovery MR750w 3T. MRI data included at least: a post-contrast (gadoterate meglumine Dotarem, Guerbet, Villepinte, France), a three-dimensional T1-weighted fast spoiled gradient recalled (FSPGR) acquisition (post-contrast 3DT1), post-contrast 3DT1, and fat-suppressed FLAIR images. Only MR images were used as inputs of the radiomics classifier. To ensure image quality, neuroradiologists analysed all the available imaging sequences. Table 2 details the MRI parameters for both machines.
Optima mr450w 1.5t
Manufactured by GE Healthcare
Sourced in United States
The Optima MR450w 1.5T is a magnetic resonance imaging (MRI) system designed by GE Healthcare. It operates at a field strength of 1.5 Tesla, providing high-quality images for medical diagnostics.
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Lab products found in correlation
5 protocols using optima mr450w 1.5t
1
Radiomics Analysis of Contrast-Enhanced MRI
2
Cardiac MRI Protocols for Acute Myocardial Injury
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CMR was performed between within 7 days of first symptoms using a Siemens Magnetom Espree® 1.5 T scanner (Erlangen, Germany) and a General Electric Optima MR450 W, 1.5 T (Milwaukee, Wisconsin, United States) using an 8-element phased-array coil. Cine-MR images in the long axis (2, 3, and 4 chambers) and in the short axis, covering the left ventricle from the base to the apex, were obtained using a fast-imaging Steady State Free Precession (SSFP) sequence. Myocardial edema was studied in matched locations using a triple inversion-recovery T2-weighted turbo spin echo sequence with fat and blood suppression inversion pulses (T2 STIR). Next, a bolus of gadolinium contrast (0.1 mmol/kg) was injected with an injector at a dose of 4 ml/s. Presence of LGE was assessed 10 min after the administration of the contrast in matched locations through the use of inversion-recovery 2D fast spoiled gradient echo sequence with an inversion time (TI) set to null normal myocardial signal (determined by TI scout sequence).
3
Influence of MRI Field Strength
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The influence of field strength was tested on two different MRI devices from the same manufacturer (General Electric): an Optima MR450w 1.5T superconducting magnet MRI installed in 2016 with a 70 cm tunnel, 32 channels, 50 cm FOV (Z axis), and gradients 40 mT SR 200 mT/m/s, and a Discovery MR750w 3T superconducting magnet MRI installed in 2012, with a 70 cm tunnel, 32 channels, 50 cm FOV (Z axis), and gradients 44 mT/m SR 200 T/m/s.
We used ‘head and neck’ coils with 32 channels with a 35 cm diameter adapted to the frequency of each MRI.
We used ‘head and neck’ coils with 32 channels with a 35 cm diameter adapted to the frequency of each MRI.
4
MRI Phantom Imaging Protocols
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A homogeneous phantom was designed to mimic cerebrospinal fluid and opacified blood vessels, while a heterogeneous phantom was designed to mimic the brain white matter. Both the homogeneous and heterogeneous phantoms were scanned by two clinical MRI scans (Optima MR450w 1.5T and Discovery MR750w 3T, both from GE Healthcare, Milwaukee, WI, USA), with different FOVs (24, 18, and 12 cm) and different matrices ( , , and pixels). Only T1 clinical sequences were considered. More details about the image acquisition devices and protocols can be found in paper [12 (link)] by Ammari et al. who studied the same phantom dataset.
5
Dual-Dose Contrast-Enhanced MRI Protocol
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Two imaging machines from the same manufacturer (General Electric, Milwaukee, USA) were used: Optima MR450w 1.5T and Discovery MR750w 3T. Table 2 details the MRI parameters for both machines. T1, T2-FLAIR, and DWI sequences were acquired first. A 0.025mmol/kg dose of gadoterate meglumine (Dotarem, Guerbet, Villepinte, France) was then injected, and a T1-weighted sequence was acquired. A second 0.075mmol/kg dose of the same GBCA was injected, and another T1 sequence with identical parameters was acquired. These two images will be called low-dose and reference contrast-enhanced T1 in the rest of the article, and abbreviated low-T1c and ref-T1c. The median delay between the acquisition of low-T1c and ref-T1c sequences was 6 minutes and 5 seconds (inter-quartile More than 20 lesions n=1 range 2 minutes and 10 seconds). Note that although our two-injection protocol cannot be considered as strictly equivalent to a single-injection one, the contrast uptake dynamics typically feature a fast wash-in followed by a slow wash-out (39) (link), suggesting that similar enhancement patterns would be produced in practice. Note also that two-injection MRI protocols are already recommended as a possible standard of care when a perfusion sequence is included, the first injection playing the role of preload bolus (40) (link).
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