DNA damage and relative mtDNA copy number data were analyzed with Statview for Windows (Version 5.0.1, SAS Institute Inc., Cary, NC) and JMP Pro for Windows (Version 11.0.0, SAS Institute Inc., Cary, NC). One- or two-factor analysis of variance (ANOVA) was used and each chemical was analyzed as an independent experiment. A p-value of less than 0.05 was considered statistically significant.
Dopaminergic neurodegeneration data were analyzed using the statistical software R version 2.12.0 (R Foundation for Statistical Computing, Vienna, Austria), Statview or JMP. The nonparametric Kruskal-Wallis test was used to test for differences between dosage levels for each chemical at each time point. Due to sparseness in the cross-tabulations of dosage levels and scores, Fisher's exact test (FET) was used when testing independence of chemical dosage levels and scores at each time point. FET was also used to analyze laser axotomy data. A p-value of less than 0.05 was considered statistically significant.
Dopaminergic neurodegeneration data were analyzed using the statistical software R version 2.12.0 (R Foundation for Statistical Computing, Vienna, Austria), Statview or JMP. The nonparametric Kruskal-Wallis test was used to test for differences between dosage levels for each chemical at each time point. Due to sparseness in the cross-tabulations of dosage levels and scores, Fisher's exact test (FET) was used when testing independence of chemical dosage levels and scores at each time point. FET was also used to analyze laser axotomy data. A p-value of less than 0.05 was considered statistically significant.