Ethylenediaminetetraacetic acid edta

Cysteine (Cys), homocysteine (HCys), N-acetyl-cysteine (Nac), γ-glutamylcysteine (γ-GluCys), glutathione (GSH), pantetheine, and glycine were purchased from Sigma (St. Louis, MO, USA). Chromatographic grade methanol was purchased from TEDIA Co. Inc. (Ohio, USA). Formic acid and ethylenediaminetetraacetic acid (EDTA) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). All other solvents and chemicals used were of analytical grade. The water used throughout the study was purified by a Milli-Q apparatus (Millipore, Bedford, MA). Stock standard solutions of Cys, HCys, Nac, γ-GluCys, GSH, and pantetheine were prepared in 1.0 mmol/L ethylenediaminetetraacetic acid (EDTA) solution containing 0.05% Formic acid at a concentration of 1.0 mmol/L.

PLGA (66–107 kDa, lactide:glycolide 75:25), gelatin (from porcine skin, Type A), and polyvinyl alcohol (PVA) were obtained from Sigma‐Aldrich (St. Louis). HepG2 cells, HUVECs, DAPI, L929, phosphate‐buffered saline (PBS), CCK‐8 working solution, annexin V‐fluorescein isothiocyanate isomer (FITC) reagent, and AO/EB were purchased from Keygen Biotech Co., Ltd (Nanjing, China). Trypsin was purchased from Amresco (Solon). DCM, ethylenediaminetetraacetic acid (EDTA), and DMF were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai). Fetal bovine serum (FBS), endothelial basal medium (F‐12K), penicillin‐streptomycin, and Dulbecco's modified Eagle medium (DMEM) were purchased from Gibco (Grand Island). DOX and Triton X‐100 were obtained from Aladdin Industrial Inc. (Shanghai, China). CIS was obtained from Meryer Chemical Technology Co., Ltd. (Shanghai). Paraformaldehyde (4%, w/v) and FITC‐phalloidin were purchased from Solarbio Life Sciences (Beijing). VE‐Cad primary polyclonal antibody, goat antirabbit IgG (H+L) secondary antibody, and cell labeling kits (Qtracker 525 and 655) were obtained from Thermo Fisher (Waltham).

Penicillium digitatum DSM 62840 was purchased from the German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig, Germany). Glucose, ethylene diamine tetraacetic acid (EDTA), 12 H₂O⋅Na₂HPO₄, 2 H₂O⋅NaH₂PO₄, and 1,10-phenanthroline were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). R-(+)-Limonene and R-(+)-α-terpineol were obtained from Sigma Chemical Company (St. Louis, MO, United States). Hydrochloride (SKF-525A) and dithiothreitol (DTT) were purchased from Shanghai Aladdin Bio-Chem Technology Co., Ltd. (Shanghai, China). Malt extract was obtained from Beijing Shuangxuan Microbe Culture Medium Products Factory (Beijing, China). Yeast extract and peptone were purchased from Beijing Aoboxing Bio-Tech Co., Ltd. (Beijing, China). Phenylmethylsulfonyl fluoride (PMSF) was purchased from Shanghai Macklin Biochemical Co., Ltd. (Shanghai, China).

Metaflumizone (240 g/L SC) was obtained from the BASF Chemical Co., Ltd. (Shanghai, China). Indoxacarb (95%), abamectin (95%), beta-cypermethrin (96.1%), chlorfluazuron (95%), chlorfenapyr (95%), diafenthiuron (98%), and chlorantraniliprole (95%) were purchased from Hubei Kangbaotai Fine-Chemicals Co., Ltd. (Wuhan, China). Spinetoram (60 g/L SC) and spinosad (25 g/L SC) were purchased from the Dow AgroSciences Co., Ltd. (Shanghai, China). BT WG-001 (16000 IU/mg) was supplied by the Hubei Biopesticide Engineering Research Center. The following were obtained from the Sigma Chemical Co., Ltd. (St. Louis, MO, USA): triphenyl phosphate (TPP, reagent grade); diethyl maleate (DEM, reagent grade); piperonyl butoxide (PBO, reagent grade); 1-chloro-2,4-dinitrobenzene (CDNB); reduced glutathione (GSH); fast blue B salt; sodium-dodecyl sulphate (SDS); dithiothreitol (DTT); eserine; phenylmethanesulfonyl fluoride (PMSF). Alpha-naphthol acetate (α-NA) and ethylene diamine tetra-acetic acid (EDTA) were purchased from the Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Reduced nicotinamide adenine dinucleotide phosphate (NADPH) was obtained from Roche Molecular Systems, Inc. (San Francisco, CA, USA). The protein-assay dye reagent was provided by Bio-Rad Laboratories, Inc. (Shanghai, China).