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Deacetylated gellan gum

Manufactured by Merck Group
Sourced in Germany, United States

Deacetylated gellan gum is a polysaccharide-based material used in various laboratory applications. It is derived from the bacterium Sphingomonas elodea and has a high molecular weight. Deacetylated gellan gum exhibits unique rheological properties, including the ability to form thermally reversible gels.

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2 protocols using deacetylated gellan gum

1

Formulation and Evaluation of Curcumin-Loaded Ophthalmic Nanomicelles

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The PEG2000-DSPE (Corden, Liestal, Swiztherland), Solutol HS 15 (BASF, Ludwigshafen, Germany), Cur, C6, deacetylated gellan gum, and Tween 80 were purchased from Sigma-Aldrich (Saint Louis, MO., USA). Tris(hydroxymethyl) aminomethane (Tris)-HCl buffer (pH 6.8 and 7.0) and mannitol were purchased from Beijing Baiardi Biotechnology Co. Ltd. (Beijing, China). Pyrene and PBS (PH 7.4) were products of Shanghai McLean Biochemical Technology Co. Ltd. (Beijing, China) and Beijing Solarbio Science & Technology Co. Ltd. (Beijing, China), respectively. HCECs were purchased from FuDan IBS Cell Center (Shanghai, China). Dulbecco’s Modified Eagle Medium (DMEM), fetal calf serum (FBS), and penicillin-streptomycin solution were purchased from Corning (New York, NY., USA). Bovine insulin and epithelial growth factor (EGF) were products of Cyagen Biosciences (Santa Clara, CA., USA). FAS eye fixer was purchased from Servicebio technology Co. Ltd. (Wuhan, China). Other chemicals and reagents were of analytical grade. New Zealand albino rabbits weighing 2–2.5 kg, devoid of any signs of ocular inflammation or gross abnormalities, were purchased from Beijing Jinmuyang Laboratory Animal Breeding Co. Ltd. (Beijing, China) ([license no: SCXK (Beijing) 2015-0005].
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2

Sourcing of Compounds for Pharmaceutical Research

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Breviscapine was purchased from Nanjing Zelang Biotechnology Co., Ltd. (Purity > 98%, Nanjing, People’s Republic of China). Scutellarin and telmisartan reference substances were obtained from the National Institute for the Control of Pharmaceutical and Biological Products (Beijing, People’s Republic of China). Tween 80 was obtained from JiangSu ChenPai Pharmaceutical Group Co. (HaiMen, People’s Republic of China). Mannitol was obtained from Chineway Pharmaceutical Tech., Co., Ltd. (Shanghai, People’s Republic of China). Deacetylated gellan gum was obtained from Sigma-Aldrich (Saint Louis, MO, USA).
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