Edc 1 3 dimethylaminopropyl 3 ethyl carbodiimide hydrochloride

Manufactured by Sisco Research Laboratories

Sourced in India

EDC [1-(3 Dimethylaminopropyl)-3-Ethyl Carbodiimide Hydrochloride] is a water-soluble coupling agent used in organic synthesis. It facilitates the formation of amide bonds between carboxylic acids and primary amines.

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Lab products found in correlation

Dimethyl sulfoxide (dmso), by Merck Group (2 mentions) N hydroxysuccinimide, by Sisco Research Laboratories (1 mentions)

2 protocols using edc 1 3 dimethylaminopropyl 3 ethyl carbodiimide hydrochloride

Erlotinib and Doxorubicin Nanoparticle Formulation

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Erlotinib (Mol wt = 393.436, purity of ≥95%) was a gift sample from Natco Pharma Ltd. UPSIDC (Dehradun, India). Doxorubicin also a gift sample from Neon Laboratories Pvt. Ltd. (Ghaziabad, India).The cinnamon biopolymer was purchased from Shree Ram Overseas (New Delhi, India). The polyvinyl alcohol (PVA) was received from Sisco Research Laboratory Pvt. Ltd. (Mumbai, India). The cross-linking agents EDC [1-(3 Dimethylaminopropyl)-3-Ethyl Carbodiimide Hydrochloride] and Sulpho-NHS [N-Hydroxysuccinimide] were received from Sisco Research Laboratories Pvt. Ltd. (Mumbai, India). The solvent, Dimethyl Sulfoxide (DMSO), was obtained from Merck Pvt. Ltd. (Mumbai, India), and acetone was obtained from SD Fine Chem Pvt. Ltd. (Mumbai, India), HPLC-grade water and other reagents were used as received.

Farheen M., Akhter M.H., Chitme H., Akhter M.S., Tabassum F., Jaremko M, & Emwas A.H. (2023). Harnessing Folate-Functionalized Nasal Delivery of Dox–Erlo-Loaded Biopolymeric Nanoparticles in Cancer Treatment: Development, Optimization, Characterization, and Biodistribution Analysis. Pharmaceuticals, 16(2), 207.

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Cinnamon Biopolymer-PVA Nanocarriers for Gefitinib and Doxorubicin

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Gefitinib (M_w = 446 g/mole,
purity
≥95%) was a gift from Natco Pharma Pvt. Ltd. (Dehradun, India).
Dox was a gift from Neon Laboratories Pvt. Ltd. (Ghaziabad, India).
Cinnamon biopolymer was purchased from Shree Ram Overseas (New Delhi,
India). Poly(vinyl alcohol) (PVA) was from Sisco Research Laboratory
Pvt. Ltd. (Mumbai, India). The cross-linking agents EDC [1-(3 dimethylaminopropyl)-3-ethyl
carbodiimide hydrochloride] and sulfo-NHS [N-hydroxysuccinimide]
were from Sisco Research Laboratories Pvt. Ltd. (Mumbai, India). The
organic solvent dimethyl sulfoxide (DMSO) was from Merck Pvt. Ltd.
(Mumbai, India). Acetone, deionized water, and HPLC-grade water were
obtained from SD Fine Chem Pvt. Ltd. (Mumbai, India). Other chemicals
and reagents were of analytical grade.

Farheen M., Akhter M.H., Chitme H., Suliman M., Jaremko M, & Emwas A.H. (2023). Surface-Modified Biobased Polymeric Nanoparticles for Dual Delivery of Doxorubicin and Gefitinib in Glioma Cell Lines. ACS Omega, 8(31), 28165-28184.

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