All immunohistochemical stains available in 22 tumors were reviewed. By using tissue microarray technique, another 19 AMLs were stained by MelanA (Labvision, clone A103, mouse monoclonal antibody, dilution 1:200), HMB45 (Cell Marque, clone hmb-45, mouse monoclonal antibody, dilution: 1:200), and SMA (Cell Marque, clone 1a4, mouse monoclonal antibody, dilution: 1:300). Two 2-mm-thick tissue cores represented the tumors. The reactions were evaluated in a semiquantitative fashion (0% positivity = negative; 1%–50% positivity = +; 51%–100% positivity = ++). The FFPE blocks were unavailable in eleven cases; hence, no immunohistochemistry was performed for these tumors.
Hmb 45
Manufactured by Cell Marque
Sourced in United States
HMB-45 is an immunohistochemistry antibody used for the detection of melanoma-associated antigen. It is a mouse monoclonal antibody that recognizes a specific glycoprotein expressed in melanocytic lesions.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using hmb 45
1
Immunohistochemical Analysis of AML Tumors
2
Melanoma Cell Differentiation Protocol
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